Results 141 to 150 of about 162,186 (348)

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

Microorganisms, 2020
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry, environment and societal development. One of the most important pathogens responsible for severe nosocomial infections is Acinetobacter baumannii, a Gram ...
C. O. Vrâncianu, I. Gheorghe, Ilda Czobor, M. Chifiriuc   +3 more
semanticscholar   +1 more source

Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010) [PDF]

, 2016
Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by acquiring mobile elements such as transposons, plasmids, and phages. In this study, we compared two genomes of A.
Blasco, L., Fernández García, L., Florido, J.P., Gato, E., López, M., Pachón Díaz, Jerónimo, Pascual Hernández, Álvaro, Rodriguez Baño, Jesus, Rueda, A   +8 more
core  

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]

, 2014
Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Bugg, Tim, Chen, Yin, Cosatti, Marialuisa, Jameson, Eleanor, Rajakumar, Kumar, Schäfer, Hendrik, Zhu, Yijun   +6 more
core   +1 more source

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu, Elizabeth K. Harmon, Justin K. Craig, Huili Yao, Kevin P. Battaile, David K. Johnson, Sandhya Subramanian, Wesley C. Van Voorhis, Mario Rivera, Scott Lovell   +9 more
wiley   +1 more source

Frequency of Metallo-β-Lactamase and Antimicrobial Resistance Patterns of Acinetobacter Baumannii in Carbapenem-Resistant Isolates from Intensive Care Units of the Hospitals in Isfahan City, Iran

مجله دانشکده پزشکی اصفهان, 2015
Background: Acinetobacter baumannii is a gram-negative non-fermenting cocobacill or cocci, which is mostly found in soil, different water sources, and many healthcare environments. It is intrinsically resistance to many antibiotics.
Jina Vazirzadeh, Parisa Behshood, Leila Heidari, Hasan Ghajavand   +3 more
doaj  

Presence of New Delhi metallo-β-lactamase gene (NDM-1) in a clinical isolate of Acinetobacter junii in Argentina [PDF]

, 2016
Here we report the presence of a clinically significant A. junii blaNDM-1 positive in a 38-year-old woman who was admitted to the emergency department with a fever and leg ulcers with signs of infection.
Almuzara, Marisa, Barberis, Claudia, Cittadini, Roxana, Del Castillo M,, Lazzaro, T., Montaña, Sabrina Daiana, Ramírez, M. S., Uong, S., Vay, Carlos Alberto   +8 more
core   +1 more source

Multidrug-Resistant Acinetobacter baumannii mediastinitis

The Journal of Infection in Developing Countries
Introduction: Mediastinitis remains one of the most serious complications of cardiac surgery. The reported incidence is 1–4%, while the related mortality varies from 10–47%. Case Presentation: A patient with triple vessel disease (TVD) was hospitalized at our clinic for coronary artery bypass graft (CABG) surgery.
Selman Dumani, Edmond Puca, Ermal Likaj, Stavri Llazo, Edlira Rruci, Vera Beca, Ali Refatllari, Arben Baboci   +7 more
openaire   +3 more sources

Multiresistant Acinetobacter baumannii ventriculitis

JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA, 2018
Among Gram-negative bacteria, Acinetobacter sp. has become an important nosocomial pathogen due to the increase in the number of multiresistant strains, and this species is responsible for a growing number of postoperative infections with a high mortality rate. The occurrence of multiresistant Gram-negative bacteria has led to an increase in the number 
Rafael Augusto Castro Santiago Brandão, Moises Heleno Vieira Braga, Lucas Alverne Freitas De Albuquerque, Paulo Pereira Christo, Marcello Penholate Faria, Baltazar Leão Reis   +5 more
openaire   +2 more sources

Refining responsive antimicrobial nanomaterials from random peptide libraries via machine learning

Responsive Materials, EarlyView.
Machine learning refines random peptide mixtures into responsive antimicrobial cocktails, yielding enhanced antibacterial efficacy and improved in vivo therapeutic effects. Abstract Antimicrobial resistance has evolved into one of the most serious threats to global public health, yet generalizable routes for refining random peptide mixtures (RPMs) into
Lin Wang, Lexuan Shi, Bocheng Xu, Lutong Zhou, Tingjun Chen, Chen Yang, Mingliang Jin, Yizhen Wang   +7 more
wiley   +1 more source

Acinetobacter baumannii Septicemia in a Recipient of an Allogeneic Hematopoietic Stem Cell Transplantation

Case Reports in Transplantation, 2012
Acinetobacter baumannii is a gram-negative, nonfermentative coccobacillus that causes infections in immunocompromised and chronically ill patients and is associated with multidrug resistance.
Khalid Ahmed Al-Anazi, Baha Abdalhamid, Zeyad Alshibani, Khalid Awad, Abdullah Alzayed, Hoda Hassan, Mohammed Alsayiegh   +6 more
doaj   +1 more source