Results 171 to 180 of about 159,303 (377)

adeABC efflux gene in Acinetobacter baumannii

New Microbes and New Infections, 2019
The antimicrobial resistance to Acinetobacter baumannii is significantly high and continues to grow; it has become a global health issue, particularly in regards to carbapenem resistance. The expression of efflux pumps is one of the major mechanisms of antibiotic resistance in A.
C. Xu, S.R. Bilya, W. Xu
openaire   +3 more sources

Antibacterial Micro/Nanorobots: Innovations, Challenges, and Future Perspectives in Combatting Infection

Nano Select, EarlyView.
Antibacterial micro/nanorobots (MNRs) represent a breakthrough in antibacterial therapy, making precise delivery of drugs to the infection site. This review systematically summarizes the material composition, actuation, and applications of MNRs in combating biofilms and drug‐resistant infections while emphasizing the existing challenges of ...
Yichao Chen, Chenlin Jiang, Chuxie Zhang, Wenqing He, Changshun Hou   +4 more
wiley   +1 more source

Early dissemination of OXA-72-producing Acinetobacter baumannii strain in Colombia: a case report

Brazilian Journal of Infectious Diseases, 2014
Nosocomial infections caused by carbapenem-resistant Acinetobacter baumannii isolates have reached epidemic levels in past decades. Currently this microorganism is responsible for outbreaks of difficult eradication and with high mortality rates worldwide.
Sandra Yamile Saavedra, Rodrigo Cayô, Ana Cristina Gales, Aura Lucia Leal, Carlos Humberto Saavedra   +4 more
doaj   +1 more source

Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii

Microbial Genomics, 2019
Acinetobacter baumannii is a nosocomial pathogen that has emerged as a global threat because of high levels of resistance to many antibiotics, particularly those considered to be last-resort antibiotics, such as carbapenems.
M. Hamidian, Steven J. Nigro
semanticscholar   +1 more source

Acinetobacter baumannii: No more a choosy intruder?

Indian Journal of Medical Sciences, 2011
Acinetobacter baumannii, a non-fermenter, is fast coming up the list of pathogens causing nosocomial infections. Earlier considered to be a harmless colonizer, or at the most, a pathogen causing mostly respiratory tract infections, it has slowly but successfully emerged as a ubiquitous pathogen causing both community as well as health care associated ...
Baishali, Chakraborty, Dibyendu, Banerjee, Banya, Chakraborty   +2 more
openaire   +2 more sources

Evaluation of the Potential Carrier and Controlled Release of Antibiotics by Zinc, Nickel, and Cobalt Ferrite Nanoparticles Encapsulated with Silica and Functionalized with Moxifloxacin Hydrochloride

Particle &Particle Systems Characterization, EarlyView.
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu, Stéfanne R. R. Ferreira, Naiara G. Cabral, Romayne P. França, Hanstter H. A. Rezende, Richard Landers, Alexandre Pancotti   +6 more
wiley   +1 more source

Structural and dynamic roles of tandem acyl carrier proteins in aryl polyene biosynthesis in carbapenem-resistant Acinetobacter baumannii. [PDF]

Protein Sci
Abstract Aryl polyenes (APEs) are critical secondary metabolites in gram‐negative pathogens, synthesized by polyketide synthases that rely on acyl carrier proteins (ACPs) as essential cofactors. Despite their importance, the structural and functional dynamics of tandem ACPs—ApeE and ApeF—have remained largely uncharacterized.
Lee CY, Son M, Lee WC, Yoo S, Choi S, Kim E, Hwang E, Kim Y.   +7 more
europepmc   +2 more sources

OXA-23 Is a Prevalent Mechanism Contributing to Sulbactam Resistance in Diverse Acinetobacter baumannii Clinical Strains [PDF]

, 2018
Yunxing Yang, Qingye Xu, Tingting Li, Ying Fu, Yue Shi, Peng Lan, Dongdong Zhao, Qiong Chen, Zhihui Zhou, Yan Jiang, Anton Y. Peleg, Yunsong Yu   +11 more
openalex   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu, Long‐Lan Shu, Tao Lu, Da‐Yu Guan, Bo‐Wen Zheng, Pan‐Hui Xiong, Yang Shen, Yu‐Cheng Yang   +7 more
wiley   +1 more source