Results 201 to 210 of about 159,303 (377)
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu +3 more
wiley +1 more source
Prognostic Factors That Affect Mortality Patients with Acinetobacter baumannii Bloodstream Infection
Chunrong Huang,1,2,* Yulian Gao,1,2,* Hongxia Lin,1– 3,* Qinmei Fan,4,* Ling Chen,1,2 Yun Feng1,2 1Department of Respiratory and Critical Care Medicine, Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai,
Huang C +5 more
doaj
Tryptophan (Trp) substitutions in short antimicrobial peptides can enhance antibacterial effects. The location of Trp residues in the peptide backbone is more important in determining biological activity against Gram‐negative bacteria compared with the number of Trps incorporated.
Christopher R. Feudale +17 more
wiley +1 more source
Objectives: Acinetobacter baumannii is an omnipresent pathogen known as a major agent in healthcare and nosocomoal-associated infections. Its ability to develop resistant pattern to the major and broad spectrum antibiotics is an important issue to be ...
Parviz Vahdani +2 more
doaj
Supersulfide biology and translational medicine for disease control
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki +3 more
wiley +1 more source

