Results 241 to 250 of about 159,303 (377)

Molecular Cloning and Functional Analysis of Holin and Endolysin From Escherichia Phage UE‐M6 as Potential Antibacterial Agents

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
We isolated phage UE‐M6 from wastewater and subsequently cloned, expressed, and purified its encoded endolysin (UE‐lysin) and holin (UE‐holin). Our results demonstrate that the combined application of UE‐lysin and UE‐holin exhibits significantly greater antibacterial activity than either protein alone, indicating a synergistic interaction between the ...
Hira Niaz, Mikael Skurnik, Fazal Adnan
wiley   +1 more source

Emergence and characteristics of hypervirulent Acinetobacter baumannii. [PDF]

open access: yesBMC Infect Dis
Shi J   +8 more
europepmc   +1 more source

The Role of Machine Learning in Addressing Antibiotic Resistance: A New Era in Infectious Disease Control

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Artificial intelligence accelerates the discovery of new antibiotics by rapidly analyzing vast chemical libraries to combat antimicrobial resistance effectively. AI systems predict antibiotic resistance trends, helping researchers design targeted therapies, and prevent the spread of multidrug‐resistant infections. ABSTRACT Antimicrobial resistance (AMR)
Akmal Zubair   +3 more
wiley   +1 more source

The extent of carbapenemase encoding genes in public genome sequences [PDF]

open access: yes, 2019
A Swart   +6 more
core  

Identification and prioritization of potential therapeutic molecules against LpxA from Acinetobacter baumannii – A computational study

open access: gold, 2023
Rameez Jabeer Khan   +9 more
openalex   +1 more source

Various Bacillus and Paenibacillus Spp. Isolated From Soil Produce Compounds With Potent Antimicrobial Activity Against Clinically Relevant Pathogens

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study identified soil‐derived Bacillus and Paenibacillus strains with broad‐spectrum antimicrobial activity, including 97% inhibition of CREs by Paenibacillus profundus. Genome mining revealed biosynthetic gene clusters (NRPSs, PKSs, RiPPs) linked to antimicrobial production, highlighting their potential in combating antibiotic resistance. Created
Michael Moran   +5 more
wiley   +1 more source

Antivirulence drugs against Acinetobacter baumannii: where do they stand? [PDF]

open access: yesWorld J Microbiol Biotechnol
Elanany AA, Khalifa AG, Attia AS.
europepmc   +1 more source

Indole‐Acetic Acid Impairs Pseudomonas aeruginosa Virulence and Alters Lung Infection in Mice

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Screening for anti‐virulence activity exerted by tryptophan catabolites on laboratory and clinical strains of Pseudomonas aeruginosa showed that Indoleacetic acid (IAA) inhibits motility and pigment production, downregulates PQS gene expression, while increases oxidative stress sensitivity.
Carlos Eduardo Dias Igídio   +13 more
wiley   +1 more source

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