Results 241 to 250 of about 159,303 (377)
Loss of essential outer membrane functions causes drug hypersensitization in Acinetobacter baumannii overexpressing multidrug efflux pumps [PDF]
Efrat Hamami +5 more
openalex +1 more source
We isolated phage UE‐M6 from wastewater and subsequently cloned, expressed, and purified its encoded endolysin (UE‐lysin) and holin (UE‐holin). Our results demonstrate that the combined application of UE‐lysin and UE‐holin exhibits significantly greater antibacterial activity than either protein alone, indicating a synergistic interaction between the ...
Hira Niaz, Mikael Skurnik, Fazal Adnan
wiley +1 more source
Emergence and characteristics of hypervirulent Acinetobacter baumannii. [PDF]
Shi J +8 more
europepmc +1 more source
Artificial intelligence accelerates the discovery of new antibiotics by rapidly analyzing vast chemical libraries to combat antimicrobial resistance effectively. AI systems predict antibiotic resistance trends, helping researchers design targeted therapies, and prevent the spread of multidrug‐resistant infections. ABSTRACT Antimicrobial resistance (AMR)
Akmal Zubair +3 more
wiley +1 more source
The extent of carbapenemase encoding genes in public genome sequences [PDF]
A Swart +6 more
core
This study identified soil‐derived Bacillus and Paenibacillus strains with broad‐spectrum antimicrobial activity, including 97% inhibition of CREs by Paenibacillus profundus. Genome mining revealed biosynthetic gene clusters (NRPSs, PKSs, RiPPs) linked to antimicrobial production, highlighting their potential in combating antibiotic resistance. Created
Michael Moran +5 more
wiley +1 more source
Antivirulence drugs against Acinetobacter baumannii: where do they stand? [PDF]
Elanany AA, Khalifa AG, Attia AS.
europepmc +1 more source
Indole‐Acetic Acid Impairs Pseudomonas aeruginosa Virulence and Alters Lung Infection in Mice
Screening for anti‐virulence activity exerted by tryptophan catabolites on laboratory and clinical strains of Pseudomonas aeruginosa showed that Indoleacetic acid (IAA) inhibits motility and pigment production, downregulates PQS gene expression, while increases oxidative stress sensitivity.
Carlos Eduardo Dias Igídio +13 more
wiley +1 more source

