Results 211 to 220 of about 897,555 (284)

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie   +12 more
wiley   +1 more source

Artificial intelligence driven diet‐intestinal microbiota‐host health integration: A four‐dimensional paradigm for advancing host wellness research

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
This graphical abstract presents a novel Diet‐Artificial Intelligence (AI)‐intestinal Microbiota–Host Health paradigm integrating microbiota‐centric pathways and an AI‐driven multi‐omics workflow. Diet shapes gut bacteria that regulate intestinal mucosal integrity, immune signaling, and gut–brain neurotransmitters to influence host health.
Tianle He   +16 more
wiley   +1 more source

Bacterial indole‐3‐butyric acid promotes fish PUFA synthesis

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
Polyunsaturated fatty acids (PUFAs) are essential nutrients in aquatic products, yet the contribution of gut microbiota‐derived metabolites to PUFA biosynthesis remains largely unknown. In this study, a gut‐derived Bacillus strain was identified to enhance PUFA accumulation via indole‐3‐butyric acid (IBA) production.
Ruojing Li   +10 more
wiley   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang   +14 more
wiley   +1 more source

Aging and periodontitis increase brain dissemination of oral bacteria

open access: yesJournal of Periodontology, Volume 97, Issue 9, Page 1965-1979, September 2026.
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu   +7 more
wiley   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait   +5 more
wiley   +1 more source

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