Results 51 to 60 of about 897,555 (284)
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
AntibioticsThe addition of sulbactam restores the complete range of cefoperazone activity against bacteria and extends its spectrum of action to include the Acinetobacter species.
Chienhsiu Huang, Lichen Lin, Sufang Kuo
doaj +1 more source
A Microcapsule‐Integrated smRandom‐seq Platform Enables Fixation‐Free Single Microbe RNA Sequencing
Advanced Science, EarlyView.We developed a microcapsule‐integrated high‐throughput fixation‐free single‐microbe RNA‐seq workflow in which microbes are encapsulated in aqueous two‐phase microcapsules for physical confinement of nucleic acids. This platform enables co‐encapsulation with barcoded beads for sequencing and reveals that fixation‐free processing enhances transcriptomic ...
Mengdi Song +5 more
wiley +1 more source
Egyptian Journal of Chest Disease and Tuberculosis, 2017 Background: Acinetobacter baumannii (A. baumannii) was considered as a leading cause of nosocomial respiratory infection and bacteremia in many hospitals all over the world. However, there was still a debates whether colonization and/ or infection with A.
Ashraf E. Sileem +2 more
doaj +1 more source
Interdisciplinary Perspectives on Infectious Diseases, 2021 Background. The emergence of multidrug-resistant (MDR) microorganisms causing infections is increasing worldwide and becoming more serious in developing countries. Among those, Acinetobacter species are becoming prominent. Objectives.
Sepide Namdari +4 more
doaj +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
Advanced Science, EarlyView.This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Investigation of the prevalence and role of mobile genetic elements associated with an aminoglycoside resistance gene, aacC2a, in Acinetobacter baumannii [PDF]
, 2009 Includes abstract. Includes bibliographical references (leaves 115-141)
Jongwe, Tsungai Ivai
core +1 more source
Epidemiological study of Acinetobacter baumannii nosocomial infections [PDF]
, 2021 Universitatea de Stat de Medicină și Farmacie „NicolaeTestemițanu”, Republica MoldovaIntroduction. Acinetobacter baumannii is a pathogen and a major cause of nosocomial infections in the current healthcare system worldwide due to its high resistance to ...
Prisacari, Viorel, Andronachi, Nicoleta
core +1 more source
Diagnosis of Acinetobacter Baumannii Infections
International Journal of Preventive Medicine, 2012 Hasan T Gozdas
doaj +2 more sources
One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections
Advanced Science, EarlyView.Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong +11 more
wiley +1 more source