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Determination of Acitretin and 13-cis-Acitretin in Skin
Skin Pharmacology, 2009The aim of the study was to investigate the concentrations of Ro 10–1670 (acitretin) and its isomeric metabolite Ro 13–7652 (cis-acitretin) after multiple oral dosing of acitretin. We used a highly sensitive HPLC method for simultaneous determination of the 2 retinoids with a quantification limit of 2 ng/ml in plasma and 10 ng/g in total skin ...
J P, Laugier +6 more
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Retrospective study of the efficacy of narrowband UVB and acitretin
Journal of Dermatological Treatment, 2003 BACKGROUND: In this retrospective analysis the effect of narrowband ultraviolet B treatment in combination with acitretin is reviewed in 40 patients with plaque psoriasis.
M Lebwohl
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Journal of Pharmaceutical Sciences, 2003 Acitretin, a retinoid for the treatment of severe psoriasis, exhibits extremely low aqueous solubility and high photosensitivity. This study investigated the effects of the complexation of acitretin with the respective hydroxypropyl-beta-cyclodextrin ...
Xin Liu, Hai-Shu Lin, Sui Yung Chan
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