Isotretinoin Exposure and Risk of Celiac Disease. [PDF]
PLoS ONE, 2015 Isotretinoin (13-cis retinoic acid) is a metabolite of vitamin A and has anti-inflammatory and immunoregulatory effects; however, a recent publication by DePaolo et al.
Shadi Rashtak +6 more
doaj +2 more sources
Skeletal Side Effects of Systemic Isotretinoin Treatment: Do They Depend on Age, Gender, Treatment Duration, Daily Dose and Isotretinoin-Naiveness? [PDF]
Dermatology Practical & Conceptual, 2023 Introduction: Systemic isotretinoin is the most effective treatment modality in acne vulgaris; however, both patients and physicians hesitate to use it due its side effects.
Defne Özkoca +5 more
doaj +2 more sources
Acta Dermato-Venereologica, 2023 Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with atopic dermatitis are affected by severe acne and isotretinoin tolerability are ...
Cathrine H. Mohn +4 more
doaj +1 more source
Premature ventricular contractions associated with isotretinoin use [PDF]
Anais Brasileiros de Dermatologia, 2016 Isotretinoin has been considered a unique drug for acne treatment. However, it is associated with numerous adverse effects. Isotretinoin can trigger premature ventricular contractions.
Sevil Alan +2 more
doaj +1 more source
Isotretinoin induced achilles tendinopathy: Histopathological and biomechanical evaluation on rats
Acta Orthopaedica et Traumatologica Turcica, 2018 Objective: The aim of the present study was to evaluate histopathological and biomechanical effects of isotretinoin on Achilles tendon. Materials & methods: Sixteen rats were divided into two groups including the control group (n = 8) and isotretinoin ...
Ozan Beytemür +5 more
doaj +1 more source
Manic symptoms associated with isotretinoin and methylphenidate combination: a case report
Psychiatry and Clinical Psychopharmacology, 2021 Isotretinoin (RoaccutaneTM) is a systemic synthetic retinoid used to treat acne vulgaris and some other dermatological diseases. Isotretinoin is associated with several psychiatric side effects.
Mehmet Akif Ersoy, Hatice Topcu Ersoy
doaj +1 more source
The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis [PDF]
Obstetrics & Gynecology Science, 2021 Objective Isotretinoin is among the most notorious human teratogens, documented originally as causing up to 30% of malformations. This systematic review and meta-analysis aimed to evaluate the rates of major malformation (MM) among isotretinoin-exposed ...
Eun Jeong Choi +10 more
doaj +1 more source
The Effects of Isotretinoin on The Menstrual Cycle: A Cross-Sectional Study
Clinics and Practice, 2022 Menstrual irregularities during isotretinoin therapy, including amenorrhea, can cause a great deal of health-status uncertainty such as the possibility of pregnancy.
Ghadah Alhetheli +8 more
doaj +1 more source
Women's experiences regarding isotretinoin risk reduction counseling in Riyadh
Journal of Dermatology and Dermatologic Surgery, 2019 Context: Isotretinoin is an effective acne treatment and a known teratogen. Contraception counseling may reduce isotretinoin-exposed pregnancies. Aims: The aim of the study is to assess the efficacy of contraception counseling in married females of ...
Shoug Algoblan +2 more
doaj +1 more source
A systematic review of isotretinoin dosing in acne vulgaris
JEADV Clinical Practice, 2023 How does low‐dose oral isotretinoin compare with recommended and high‐dose oral isotretinoin in terms of efficacy, adverse effect profile, duration of remission, economic profile and rate and severity of relapse? A systematic literature search of EMBASE,
Aoife U. Daly +8 more
doaj +1 more source