Results 31 to 40 of about 10,975 (186)

Compliance with Pregnancy Prevention Recommendations for Isotretinoin Following the Amendment of the European Union Pregnancy Prevention Program: A Repeat Study in Estonia

Drugs - Real World Outcomes, 2023
Background Isotretinoin, indicated for severe acne, is a potent teratogen and therefore contraindicated in pregnancy. Thus, the pregnancy prevention program (PPP) for isotretinoin has been introduced.
Maaja Ivask, Katrin Kurvits, Maia Uusküla, Anne Juppo, Ott Laius, Mia Siven   +5 more
doaj   +1 more source

Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana, Thambaramala V. Gamage, Tanoj K. Singh, Shuaifei Zhao, Amy Logan, Lingxue Kong   +5 more
wiley   +1 more source

Prevention of Isotretinoin-Induced Oxidative Stress and Hepatotoxicity [PDF]

MATEC Web of Conferences
Isotretinoin, also known as 13-cis-retinoic acid, is one of the most recognized treatments for the skin disease acne vulgaris, which is largely attributed to its high rates of success and overall effectiveness.
Xinyue Xu Catherine
doaj   +1 more source

The Association between Adiponectin Single Nucleotide Polymorphisms and Side Effects of Isotretinoin in Acne Patients

Dermatology Research and Practice, 2020
Background. Acne is a common condition of pilosebaceous follicle especially among young. Clinically, the most used medication in the treatment of moderate to severe acne is oral isotretinoin.
Munir Garba, Omar F. Khabour, Karem H. Alzoubi, Ahmed Abu-Siniyeh, Firas Al-Qarqaz   +4 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Hypoacusia in a Patient Treated by Isotretinoin

Case Reports in Medicine, 2011
Isotretinoin is the most effective treatment for severe acne, but there are several adverse effects associated with its use, some of them very exceptional (
L. Rosende, M. M. Verea-Hernando, A. de Andrés, F. Piñeyro-Molina, J. Barja, S. Castro-Castro, E. Fonseca   +6 more
doaj   +1 more source

Comparative study between Isotretinoin Alone versus Isotretinoin Combined with Either Levocetirizine or Desloratadine in The Treatment of Acne Vulgaris [PDF]

International Journal of Medical Arts
Background: Many studies have proved isotretinoin's effectiveness in the treatment of acne. However, because of the potential for mucocutaneous side effects and acne outbreaks, it should be used and monitored with caution. To avoid undesired side effects,
Ebtihal Elsekily, Emad Elgmal, Hany Aboelwafa   +2 more
doaj   +1 more source

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

JEADV Clinical Practice, EarlyView.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro, Flaminia Antonelli, Dalma Malvaso, Federica Pellegrini, Elena Ippoliti, Niccolò Gori, Ketty Peris   +6 more
wiley   +1 more source

Isotretinoin Use in Transmasculine Patients and Its Implication on Chest Masculinization Surgery: Scoping Review of the Literature

JMIR Dermatology, 2023
BackgroundAcne often worsens in transmasculine patients who are on prolonged testosterone therapy. Isotretinoin is an oral retinoid used in the treatment of severe or refractory cases of acne, but it has the potential to cause ...
Daniel Strock, Torunn E Sivesind, Robert P Dellavalle, Gerhard S Mundinger   +3 more
doaj   +1 more source

Early Acitretin Therapy in a Patient With Harlequin Ichthyosis

JEADV Clinical Practice, EarlyView.
ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark, Parith Wongkittichote, Sanchawan Wittayakornrerk   +2 more
wiley   +1 more source