Background Isotretinoin, indicated for severe acne, is a potent teratogen and therefore contraindicated in pregnancy. Thus, the pregnancy prevention program (PPP) for isotretinoin has been introduced.
Maaja Ivask +5 more
doaj +1 more source
Introduction: This study aimed to evaluate the effect of oral isotretinoin therapy on nasal dryness and nasal obstruction in patients with acne vulgaris. Methods: A total of 102 patients with acne vulgaris (mean ± standard deviation age, 21.1±3.4 years;
Enes Yiğit +4 more
doaj +1 more source
Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. [PDF]
13-cis-retinoic acid (isotretinoin, INN) is an oral pharmaceutical drug used for the treatment of skin acne, and is also a known teratogen. In this study, the molecular mechanisms underlying INN-induced developmental toxicity during early cardiac ...
Geller, Benjamin S +9 more
core +3 more sources
Comparative study between Isotretinoin Alone versus Isotretinoin Combined with Either Levocetirizine or Desloratadine in The Treatment of Acne Vulgaris [PDF]
Background: Many studies have proved isotretinoin's effectiveness in the treatment of acne. However, because of the potential for mucocutaneous side effects and acne outbreaks, it should be used and monitored with caution. To avoid undesired side effects,
Ebtihal Elsekily +2 more
doaj +1 more source
Analysis of common oral and topical dermatologic medication price variation by source [PDF]
Online coupon retailers and pharmacies are popular sites that patients can access discounted medications when compared to cash prices. These sources are especially important for those patients without insurance.
Boyko, Alexander, Smith, Gideon P
core
Hidradenitis suppurativa (HS) is often diagnosed late, complicating management. In this nationwide Danish study including 10,196 patients with dermatologist‐verified HS, we examined treatment patterns before and after referral to specialised hospital care.
Nana A. L. Rosenø +8 more
wiley +1 more source
How are Acne Vulgaris Patients Using Oral Isotretinoin Affected by COVID-19?
Introduction: It has been reported that the use of oral isotretinoin may have positive and negative effects on the course of COVID-19 and the risk of transmission.
Mine Müjde Kuş +6 more
doaj +1 more source
Laboratory tests in patients treated with isotretinoin: occurrence of liver and muscle abnormalities and failure of AST and ALT to predict liver abnormality. [PDF]
Current laboratory monitoring may not be optimal. A retrospective chart review was performed on thelaboratory results of 246 patients who were treated with isotretinoin for acne over a 9-year period.
Grimes, Lorraine R. +2 more
core +1 more source
Obsessive-compulsive disorder with bipolar diathesis following isotretinoin therapy remitting upon treatment with olanzapine and fluvoxamine [PDF]
Isotretinoin, a drug used for moderate to severe acne, has been repeatedly associated with various psychiatric complications, although a definitive causal relationship has not been established to date.
Fornaro, Michele
core +2 more sources
Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos +2 more
wiley +1 more source

