Comprehensive review of reports of menstrual irregularities associated with isotretinoin
In 1982, oral isotretinoin was first licensed as a treatment option for severe recalcitrant cystic acne in the United States. Since its introduction into the pharmaceutical market, several instances of amenorrhea in women of child-bearing age taking ...
Priya Chelliah, BA +1 more
doaj +1 more source
Premature ventricular contractions associated with isotretinoin use [PDF]
Isotretinoin has been considered a unique drug for acne treatment. However, it is associated with numerous adverse effects. Isotretinoin can trigger premature ventricular contractions.
Sevil Alan +2 more
doaj +1 more source
Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development [PDF]
Muir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of ...
Graefe, Tim +3 more
core +1 more source
Combination of naltrexone and isotretinoin for the treatment of darier disease
Darier disease (DD) is an autosomal-dominant genodermatosis in which mutations in the ATP2A2 gene result in impaired intercellular adhesion and epidermal blistering.
Costa, Tomás +3 more
core +1 more source
Isotretinoin induced achilles tendinopathy: Histopathological and biomechanical evaluation on rats
Objective: The aim of the present study was to evaluate histopathological and biomechanical effects of isotretinoin on Achilles tendon. Materials & methods: Sixteen rats were divided into two groups including the control group (n = 8) and isotretinoin ...
Ozan Beytemür +5 more
doaj +1 more source
Background Peanut and soybean allergies are listed as contraindication in the package leaflet of isotretinoin, a widely used treatment of acne vulgaris.
Anna Bamidis, Silke C. Hofmann
doaj +1 more source
The Effects of Isotretinoin on The Menstrual Cycle: A Cross-Sectional Study
Menstrual irregularities during isotretinoin therapy, including amenorrhea, can cause a great deal of health-status uncertainty such as the possibility of pregnancy.
Ghadah Alhetheli +8 more
doaj +1 more source
A systematic review of isotretinoin dosing in acne vulgaris
How does low‐dose oral isotretinoin compare with recommended and high‐dose oral isotretinoin in terms of efficacy, adverse effect profile, duration of remission, economic profile and rate and severity of relapse? A systematic literature search of EMBASE,
Aoife U. Daly +8 more
doaj +1 more source
Manic symptoms associated with isotretinoin and methylphenidate combination: a case report
Isotretinoin (RoaccutaneTM) is a systemic synthetic retinoid used to treat acne vulgaris and some other dermatological diseases. Isotretinoin is associated with several psychiatric side effects.
Mehmet Akif Ersoy, Hatice Topcu Ersoy
doaj +1 more source
The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis [PDF]
Objective Isotretinoin is among the most notorious human teratogens, documented originally as causing up to 30% of malformations. This systematic review and meta-analysis aimed to evaluate the rates of major malformation (MM) among isotretinoin-exposed ...
Eun Jeong Choi +10 more
doaj +1 more source

