Results 11 to 20 of about 19,183 (269)

Tear Film and Ocular Surface Changes in Patients Receiving Systemic Isotretinoin

, 2013
Purpose: Our aim in this study was to assess the ocular surface and tear film changes in acne vulgaris patients receiving systemic isotretinoin. Material and Method: Twenty-two eyes of 22 patients who received oral isotretinoin (roaccutane®, 0.7 mg/kg ...
Berna Şanlı, Yaylalı, Volkan, Şanlı, Berna, Ferda Bir, Nida Kaçar, Volkan Yaylalı, Yaldızkaya, Filiz, Kaçar, Nida, Çetin, Ebru Nevin, Ebru Nevin Çetin, Bir, Ferda, Filiz Yaldızkaya   +11 more
core   +2 more sources

Isotretinoin (13-cis-retinoic acid)-associated premature ventricular contractions

The Turkish Journal of Pediatrics, 2009
Isotretinoin (13-cis-retinoic acid), a synthetic vitamin A derivative, is used to treat a wide variety of dermatologic conditions including severe acne. Isotretinoin can trigger premature ventricular contractions (PVCs).
Esra Kiliç, Murat Sahin, Sedef Sahin, Sema Ozer   +3 more
doaj   +2 more sources

Community pharmacists’ knowledge and awareness about isotretinoin therapy and its dispensing practice in Jordan

Heliyon, 2023
A validated self-reported questionnaire was used to evaluate pharmacists' knowledge about isotretinoin and their awareness of isotretinoin dispensing practice.
Anan S. Jarab, Sayer I. Al-Azzam, Shriefa Al-Mutairi, Shrouq Abu Heshmeh, Tareq L. Mukattash, Walid AL-Qerem, Rami Beiram, Salah Aburuz   +7 more
doaj   +1 more source

Histological effect of high versus low dose isotretinoin and possible protective role of Tiron on skin of adult male albino rat [PDF]

The Egyptian Journal of Histology, 2019
Background: Isotretinoin is one of the most effective drugs in acne treatment. It is retinoic acid derivative. Systemic administration of isotretinoin may induce many adverse effects.
Maha Soliman, Hala El-Haroun, Maisa Kafafy, doaa mohamed   +3 more
doaj   +1 more source

Prevalence and associated risk factors of acne relapse among Saudi acne vulgaris patients using isotretinoin

Saudi Pharmaceutical Journal, 2020
Background: Acne vulgaris is a self-limiting condition that may affect the patients quality of life. The most efficacious treatment of choice for acne is isotretinoin.
Alshammari SA, Alamri Y, Alanazi AM, Almuhanna SA, Pinjabi L, Alsnaidi NA   +5 more
doaj   +1 more source

Isotretinoin Hepatotoxicity or Isotretinoin Induced Autoimmune Hepatitis?

Indian Journal of Paediatric Dermatology, 2021
While isotretinoin, a drug used for the treatment of severe nodulocystic acne, is known to be hepatotoxic, an association with autoimmune hepatitis (AIH) has not been suggested so far.
Fatma Ilknur Varol, Mukadder Ayse Selimoglu, Nese Karadag, Sukru Gungor   +3 more
doaj   +1 more source

Comparative Pharmacokinetic Profiles of a Novel Low-dose Micronized-isotretinoin 32 mg Formulation and Lidose-isotretinoin 40 mg in Fed and Fasted Conditions: Two Open-label, Randomized, Crossover Studies in Healthy Adult Participants

Acta Dermato-Venereologica, 2020
Two open-label, crossover studies compared the bioavailability of Micronized-isotretinoin 32 mg and Lidose-isotretinoin 40 mg in healthy adults. In the fed bioequivalence/food-effect study, participants (n = 71) received single doses of fed-state ...
Sumit Madan, Sudershan Kumar, Jeanett Segal   +2 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Isotretinoin exposure in pregnant women in Korea [PDF]

Obstetrics & Gynecology Science, 2018
ObjectiveIsotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program (PPP); however, no PPP has yet been ...
Nae Ry Kim, So Ra Yoon, June Seek Choi, Hyun Kyong Ahn, So-Young Lee, Dal Soo Hong, Jeong Sup Yun, Seong Yeon Hong, Yoon Ha Kim, Jung Yeol Han   +9 more
doaj   +1 more source

Prevalence of Isotretinoin Therapy in Adolescents and Young Adults With and Without Atopic Dermatitis: A Nationwide Prescription-based Population Study

Acta Dermato-Venereologica, 2023
Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with atopic dermatitis are affected by severe acne and isotretinoin tolerability are ...
Cathrine H. Mohn, Hege S. Blix, Anja Maria Brænd, Per Nafstad, Jon Anders Halvorsen   +4 more
doaj   +1 more source