Tretinoin for Photodamaged Facial Skin: Systematic Review and Meta-Analysis of Randomized Controlled Trials [PDF]
Introduction: Randomized controlled trials have suggested that tretinoin, a topical retinoid, can improve wrinkling in photodamaged skin; however, its overall effectiveness remains subject of debate.
Hsin-Yin Huang, Leon Tsung-Ju Lee
doaj +2 more sources
Comparison of the Efficacy of Kligman's Formula Combined With 30% Topical Metformin Versus Kligman's Formula Alone in the Treatment of Melasma [PDF]
ABSTRACT Background Melasma is a common hyperpigmentation disorder primarily affecting women, influenced by ultraviolet exposure, hormones, and genetics. Kligman's formula is a first‐line therapy, but emerging evidence suggests that topical metformin, an antidiabetic with antimelanogenic effects, may enhance treatment outcomes.
Iraji F +4 more
europepmc +2 more sources
Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis [PDF]
Chronic ultraviolet (UV) exposure is the primary cause of skin photoaging, leading to wrinkles, pigmentation changes, and loss of dermal elasticity. This systematic review and network meta-analysis evaluated the efficacy and safety of topical compounds ...
Lulu Lin +12 more
doaj +2 more sources
EPRI approach on studying deep skin penetration of tretinoin-containing liposomes [PDF]
Introduction: Tretinoin has a variety of skin-beneficial properties. However, when used at the dosages required to get the best outcomes, it also has significant adverse effects.
Stojković Tamara D. +4 more
doaj +1 more source
Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials
Background:. Aging, an inevitable and continuous process in one’s lifetime, has all along been a focus of interest, especially for women, yet photoaging treatment to slow the process remains challenging.
Irma Bernadette S. Sitohang, MD, PhD +3 more
doaj +1 more source
With immune checkpoint therapy (ICT) having reshaped the treatment of many cancers, the next frontier is to identify and develop novel combination therapies to improve efficacy. Previously, we and others identified beneficial immunological effects of the
Caitlin M. Tilsed +20 more
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Human papilloma virus (HPV) is capable of causing varieties of dermatological conditions differing in morphology, histopathology and site of occurrence.
Rashmi Singh, Shyam Sundar Pandey
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Long-term follow-up results of cytarabine-containing chemotherapy for acute promyelocytic leukemia [PDF]
Background/Aims We evaluated the feasibility and long-term efficacy of the combination of cytarabine, idarubicin, and all-trans retinoic acid (ATRA) for treating patients with newly diagnosed acute promyelocytic leukemia (APL).
Young Hoon Park +36 more
doaj +1 more source
Fabrication and characterization of tretinoin-loaded nanofiber for topical skin delivery
Background Tretinoin or all-trans retinoic acid is used in the treatment of acne vulgaris and photo-aging. This work aims to develop tretinoin-loaded nanofibers as a potential anti-acne patch and to investigate its physicochemical characteristics. Method
Saba Khoshbakht +3 more
doaj +1 more source
The role of local retinoids in eliminating signs of skin aging [PDF]
Skin aging is a complex process involving both internal (chronological aging) and external (biological aging) factors. Slowing down the proliferative and immune processes in the epidermis, reducing the activity of fibroblasts and vascularization of the ...
Vera I. Albanova
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