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Liposomes: structure, composition, types, and clinical applications
Heliyon, 2022 Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity.
Hamdi Nsairat, Usamah Sayed, Fadwa Odeh
exaly +4 more sources
Design of liposomes as drug delivery system for therapeutic applications
International Journal of Pharmaceutics, 2021 Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent a powerful delivery system for several drugs.
Diana Guimarães +2 more
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Liposomes: Advancements and innovation in the manufacturing process
Advanced Drug Delivery Reviews, 2020 Liposomes are well recognised as effective drug delivery systems, with a range of products approved, including follow on generic products. Current manufacturing processes used to produce liposomes are generally complex multi-batch processes. Furthermore,
Vivek Dhawan, René Holm, Yvonne Perrie
exaly +2 more sources
Polymer-Modified Liposomes for Drug Delivery: From Fundamentals to Applications
Pharmaceutics, 2022 Liposomes are highly advantageous platforms for drug delivery. To improve the colloidal stability and avoid rapid uptake by the mononuclear phagocytic system of conventional liposomes while controlling the release of encapsulated agents, modification of ...
Yifeng Cao, Xinyan Dong, Xuepeng Chen
doaj +2 more sources
Liposomes as nanomedical devices
International Journal of Nanomedicine, 2015 Since their discovery in the 1960s, liposomes have been studied in depth, and they continue to constitute a field of intense research. Liposomes are valued for their biological and technological advantages, and are considered to be the most successful ...
Giuseppina Bozzuto, Agnese Molinari
exaly +2 more sources
Antibodies induced by antigen-containing liposomes as immunogens preferentially recognize their antigens present on lipid vesicles [PDF]
Scientific ReportsWe established a flow cytometry method to detect interactions between antibodies against glycosphingolipids (GSLs) and liposomes composed of phospholipids, cholesterol, and GSLs.
Tetsuya Okuda, Michiyo Maruyama
doaj +2 more sources
Advances in liposome research in the field of antitumor [PDF]
BIO Web of Conferences, 2023 Liposomes, as biocompatible and safe nanocarriers with easily modified surfaces, can be well used in the field of antitumor. Their targeting properties have contributed to the reduction of drug dosage and non-target cell toxicity.
Xu Xiaochuang
doaj +1 more source
Dual Role of Vitamin C-Encapsulated Liposomal Berberine in Effective Colon Anticancer Immunotherapy
Pharmaceuticals, 2023 The aim of the study was to achieve effective colon anticancer immunotherapy using the alkaloid berberine. In the presented paper we attempt to develop a formulation of berberine loaded into liposomal carriers using the vitamin C gradient method ...
Martyna Mianowska +5 more
doaj +1 more source
Pharmaceutics, 2023 Pancreatic cancer (PC) is one of the deadliest cancers so there is an urgent need to develop new drugs and therapies to treat it. Liposome-based formulations of naturally-derived bioactive compounds are promising anticancer candidates due to their ...
Adam Markowski +7 more
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Molecules, 2022 Liposomes have been considered promising and versatile drug vesicles. Compared with traditional drug delivery systems, liposomes exhibit better properties, including site-targeting, sustained or controlled release, protection of drugs from degradation ...
Peng Liu, Guiliang Chen, Jingchen Zhang
semanticscholar +1 more source