Synthesis and Antioxidant Activity of Caffeic Acid Derivatives
Molecules, 2018 A series of caffeic acid derivatives were synthesized via a modified Wittig reaction which is a very important tool in organic chemistry for the construction of unsaturated carbon–carbon bonds.
Katarzyna Sidoryk +4 more
doaj +1 more source
Novel Findings about Double-Loaded Curcumin-in-HPβcyclodextrin-in Liposomes: Effects on the Lipid Bilayer and Drug Release [PDF]
, 2018 In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes (DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL–DL.
Fernández Romero, Ana María +4 more
core +2 more sources
MiR-219a-5p Enriched Extracellular Vesicles Induce OPC Differentiation and EAE Improvement More Efficiently Than Liposomes and Polymeric Nanoparticles [PDF]
, 2020 Remyelination is a key aspect in multiple sclerosis pathology and a special effort is being made to promote it. However, there is still no available treatment to regenerate myelin and several strategies are being scrutinized.
Alberro, Ainhoa +17 more
core +3 more sources
Frontiers in Immunology, 2018 Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8+ T-cells, a key response for the clearance of intracellular pathogens and tumors.
Yoelys Cruz-Leal +11 more
doaj +1 more source
Hydrophobic cis-platinum complexes efficiently incorporated into liposomes [PDF]
, 1992 The present invention involves the synthesis and use of new platinum compounds. These new platinum compounds are easy to encapsulate in liposomes at high efficiencies.
Khokhar, Abdul R. +2 more
core +3 more sources
Drug Delivery, 2020 Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and mortality. In this study, a novel myocardial targeted drug delivery system was developed represented by co-modified liposomes consisting of red cell membrane (RCM), and ...
Xueyan Liu +7 more
doaj +1 more source
Immunological and Toxicological Considerations for the Design of Liposomes
Nanomaterials, 2020 Liposomes hold great potential as gene and drug delivery vehicles due to their biocompatibility and modular properties, coupled with the major advantage of attenuating the risk of systemic toxicity from the encapsulated therapeutic agent.
Collin T. Inglut +6 more
semanticscholar +1 more source
Journal of Nanobiotechnology, 2021 Liposomes are widely used as drug delivery carriers and as cell model systems. Here, we measure the dielectric properties of individual liposomes adsorbed on a metal electrode by in-liquid scanning dielectric microscopy in force detection mode.
Martina Di Muzio +5 more
doaj +1 more source
Comparative studies of the preparation of immunoliposomes with the use of two bifunctional coupling agents and investigation of in vitro immunoliposome-target cell binding by cytofluorometry and electron microscopy [PDF]
, 1990 The two coupling agents SPDP (N-succinimidyl-3-(2-pyridyldithio)propionate) and SATA (N-succinimidyl-S-acetylthioacetate) were compared in their efficiency and feasibility to couple monoclonal antibodies (Abs) via thioether linkage to liposomes ...
Berinstein +34 more
core +1 more source
Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment [PDF]
, 2020 BACKGROUND: Docetaxel chemotherapy in prostate cancer has a modest impact on survival. To date, efforts to develop combination therapies have not translated into new treatments. We sought to develop a novel therapeutic strategy to tackle chemoresistant
Dufès, Christine +9 more
core +3 more sources