Results 11 to 20 of about 111,537 (264)

Folate-Targeted Nanoliposomal Chemophototherapy

Pharmaceutics, 2023
Light-responsive liposomes have been developed for the on-demand release of drugs. However, efficient delivery of chemotherapeutic drugs to tumor for cancer theranostics remains a challenge.
Upendra Chitgupi, Yiru Qin, Sanjana Ghosh, Breandan Quinn, Kevin Carter, Xuedan He, Ulas Sunar, Jonathan F. Lovell   +7 more
doaj   +1 more source

Synthesis and Antioxidant Activity of Caffeic Acid Derivatives

Molecules, 2018
A series of caffeic acid derivatives were synthesized via a modified Wittig reaction which is a very important tool in organic chemistry for the construction of unsaturated carbon–carbon bonds.
Katarzyna Sidoryk, Anna Jaromin, Nina Filipczak, Piotr Cmoch, Marcin Cybulski   +4 more
doaj   +1 more source

Enhanced active targeting via cooperative binding of ligands on liposomes to target receptors. [PDF]

PLoS ONE, 2013
To achieve effective active targeting in a drug delivery system, we previously developed dual-targeting (DT) liposomes decorated with both vascular endothelial growth factor receptor-1 (VEGFR-1)-targeted APRPG and CD13-targeted GNGRG peptide ligands for ...
Tomoki Sugiyama, Tomohiro Asai, Yuki Murase Nedachi, Yasufumi Katanasaka, Kosuke Shimizu, Noriyuki Maeda, Naoto Oku   +6 more
doaj   +1 more source

The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes

Frontiers in Immunology, 2018
Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8+ T-cells, a key response for the clearance of intracellular pathogens and tumors.
Yoelys Cruz-Leal, Daniel Grubaugh, Catarina V. Nogueira, Isbel Lopetegui-González, Anaixis del Valle, Felipe Escalona, Rady J. Laborde, Carlos Alvarez, Luis E. Fernández, Michael N. Starnbach, Darren E. Higgins, María E. Lanio   +11 more
doaj   +1 more source

In vitro and in vivo evaluation of liposomes modified with polypeptides and red cell membrane as a novel drug delivery system for myocardium targeting

Drug Delivery, 2020
Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and mortality. In this study, a novel myocardial targeted drug delivery system was developed represented by co-modified liposomes consisting of red cell membrane (RCM), and ...
Xueyan Liu, Liangke Zhang, Wengao Jiang, Zhangyou Yang, Zongjie Gan, Chao Yu, Ran Tao, Huali Chen   +7 more
doaj   +1 more source

Dielectric properties and lamellarity of single liposomes measured by in-liquid scanning dielectric microscopy

Journal of Nanobiotechnology, 2021
Liposomes are widely used as drug delivery carriers and as cell model systems. Here, we measure the dielectric properties of individual liposomes adsorbed on a metal electrode by in-liquid scanning dielectric microscopy in force detection mode.
Martina Di Muzio, Ruben Millan-Solsona, Aurora Dols-Perez, Jordi H. Borrell, Laura Fumagalli, Gabriel Gomila   +5 more
doaj   +1 more source

Polymer-Modified Liposomes for Drug Delivery: From Fundamentals to Applications

Pharmaceutics, 2022
Liposomes are highly advantageous platforms for drug delivery. To improve the colloidal stability and avoid rapid uptake by the mononuclear phagocytic system of conventional liposomes while controlling the release of encapsulated agents, modification of ...
Yifeng Cao, Xinyan Dong, Xuepeng Chen
doaj   +1 more source

Camptothecin-Loaded Liposomes with α-Melanocyte-Stimulating Hormone Enhance Cytotoxicity Toward and Cellular Uptake by Melanomas: An Application of Nanomedicine on Natural Product

Journal of Traditional and Complementary Medicine, 2013
In this study, we attempted to develop functional liposomes loaded with camptothecin and attached to α-melanocyte-stimulating hormone (α-MSH) to target melanoma cells.
Chih-Hung Lin, Saleh A. Al-Suwayeh, Chih-Feng Hung, Chih-Chieh Chen, Jia-You Fang   +4 more
doaj   +1 more source

Effects of the protein corona on liposome-liposome and liposome-cell interactions.

International journal of nanomedicine, 2016
A thorough understanding of interactions occurring at the interface between nanocarriers and biological systems is crucial to predict and interpret their biodistribution, targeting, and efficacy, and thus design more effective drug delivery systems. Upon intravenous injection, nanoparticles are coated by a protein corona (PC).
Corbo, C, Molinaro, R, Taraballi, F, Toledano, NE, Sherman, MB, Parodi, A, Salvatore, F, Tasciotti, E   +7 more
openaire   +3 more sources

Liposomes in drugs, nutraceuticals, and cosmetics [PDF]

PeerJ
Background Liposomes are spherical vesicular structures formed by lipid bilayers with a hydrophilic internal nucleus. The size varies from about 20 nanometers to several micrometers.
Eleaneth Baltodano Viales, Gustavo Alonso Carazo Berrocal, Jorge Andrés Pacheco Molina, Fredy Barrantes Pérez, German Leonardo Madrigal Redondo   +4 more
doaj   +2 more sources