Results 51 to 60 of about 20,440 (218)
BackgroundAcne often worsens in transmasculine patients who are on prolonged testosterone therapy. Isotretinoin is an oral retinoid used in the treatment of severe or refractory cases of acne, but it has the potential to cause ...
Daniel Strock +3 more
doaj +1 more source
Isotretinoin exposure during pregnancy: A population-based study in the Netherlands [PDF]
Objective: To estimate isotretinoin exposure in Dutch pregnant women despite the implemented pregnancy prevention programme (PPP) and second, to analyse the occurrence of adverse fetal or neonatal outcomes in these isotretinoin exposed pregnancies.Design:
Herings, R.M.C. (Ron) +6 more
core +1 more source
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease characterised by painful nodules, abscesses, and draining and non‐draining tunnels. Currently, there are two biologics approved in Canada for the treatment of moderate‐to‐severe HS, adalimumab (anti‐TNF) and secukinumab (anti‐IL‐17A).
Irina Turchin +4 more
wiley +1 more source
Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing [PDF]
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds de novo.
Martínez Sayé, Melisa Soledad +5 more
core +1 more source
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro +6 more
wiley +1 more source
Psychiatric and Developmental Effects of Isotretinoin (Retinoid) Treatment for Acne Vulgaris
: Background: An association between isotretinoin (13-cis-retinoic acid, sold under trade names including Accutane [Hoffmann-La Roche Inc, Basel, Switzerland]) and birth defects, depression, and suicide is well documented but controversial.
Alessandra Suuberg, JD
doaj +1 more source
A 65-year experience treating acne, including 26 years with oral isotretinoin [PDF]
Este artigo especial foi extraído de uma palestra proferida pelo Prof. Sebastião Sampaio e elaborado em conjunto com a Profa Edileia Bagatin. Reflete a experiência dos autores no tratamento das principais formas de acne nos períodos pré e pós a ...
BAGATIN, Edileia +1 more
core +3 more sources
Effects of Isotretinoin treatment on human body - review
Introduction: Isotretinoin (13-cis-Retinoic Acid) is a part of the retinoid group, and is used in dermatology for the treatment of acne, due to its demonstrated inhibitory effect on sebaceous gland activity and proliferation.
Adam Słomczyński +6 more
doaj +1 more source
Early Acitretin Therapy in a Patient With Harlequin Ichthyosis
ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark +2 more
wiley +1 more source
Background. Acne is a common condition of pilosebaceous follicle especially among young. Clinically, the most used medication in the treatment of moderate to severe acne is oral isotretinoin.
Munir Garba +4 more
doaj +1 more source

