Results 51 to 60 of about 15,484 (216)

Therapeutic Challenges in Managing Coexisting Hidradenitis Suppurativa and Squamous Cell Carcinoma: A Clinical Case Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder affecting intertriginous areas. Long‐standing HS can undergo malignant transformation into squamous cell carcinoma (SCC), particularly in the perineal and gluteal regions. We report a 54‐year‐old man with severe, treatment‐refractory HS complicated by an aggressive verrucous
Michael Zolotas, Tereza Jakovljevicova, Kamran Ghoreschi, Kerstin Kusch, Marisa Klemp, Robert Sabat, Georgios Kokolakis   +6 more
wiley   +1 more source

Isotretinoin-induced inflammatory bowel disease

, 2006
Three case reports on inflammatory bowel disease associated with use of isotretinoin are described. All three patients were male adolescents, in good health when starting isotretinoin (for acne treatment for about six months).
Srivastava, N, van Puijenbroek, E P; id_orcid, Passier, J L M   +2 more
core   +2 more sources

Method Development and Characterization of Liposomal Formulation of Isotretinoin

, 2021
This study aims to develop a liposomal drug delivery system of isotretinoin, an acne drug-using spray drying, as a cost-effective and time-effective technique. The liposomal formulation was prepared by using spray drying; three different strategies ...
Kumar, Nitin, Kumar, N. (Nitin), Kumar, Punet, Singh, S. (Sangam), Ahmad, M. I. (Md), Ahmad, Md Iftekhar, Kumar, P. (Punet), Singh, Sangam, Punet Kumar, Sangam Singh, Nitin Kumar, Md Iftekhar Ahmad   +11 more
core   +1 more source

Subcorneal Pustular Dermatosis, a Systematic Review and Pooled Analysis of a Rare and Underdiagnosed Disease

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Subcorneal pustular dermatosis (SPD), or Sneddon–Wilkinson disease, is a rare, relapsing pustular skin condition of unknown cause, characterised by subcorneal pustules. Objectives To summarise the demographic, clinical, histopathological, management and disease course of SPD.
Mason H. Crossman, Jeffrey Weng, Alysha Vuong, Lawrence Lin, Zhao Feng Liu, Christopher Y. Chew   +5 more
wiley   +1 more source

Targeted Isotretinoin in Neuroblastoma: Kinetics, Genetics, or Absorption [PDF]

, 2013
Isotretinoin (13-cis-retinoic acid; 13-cisRA) has been shown to significantly improve survival for children with high-risk neuroblastoma. Pharmacokinetics of isotretinoin may be negatively affected by the mode of drug administration and the dosing ...
Matthay, Katherine K
core   +1 more source

Combination of chemical peels and oral isotretinoin in the treatment of acne scars [PDF]

Surgical & Cosmetic Dermatology
INTRODUCTION: Acne is a prevalent chronic disease that can cause physical, emotional, and social effects. Isotretinoin and chemical peels are available as treatment, but their combination has historically been avoided due to reports of abnormal healing ...
Marina Soares Silverio, Daniel Simão de Andrade, Carolina Malavassi Murari, Rossana Cantanhede Farias de Vasconcelos, Fernanda Rytenband   +4 more
doaj   +1 more source

Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense, Nicole Bavaro, Aashna Farishta, Jiaqi Chen, Raj Chovatiya   +4 more
wiley   +1 more source

Therapeutic dosage of isotretinoin in rats may influence orthodontic tooth movement

Bone Reports
Objective Isotretinoin, also known as 13-cis-retinoic acid, is an isomer of tretinoin, the oxidized form of Vitamin A. Orthodontic tooth movement (OTM) is the result of a cascade of inflammatory responses stimulated by a physical element that is the ...
Mayra Fernanda Ferreira, Alberto Carlos Botazzo Delbem, Edilson Ervolino, Luy de Abreu Costa, Cristina Antoniali Silva, José Ricardo Prando dos Santos, Marcos Rogério de Mendonça   +6 more
doaj   +1 more source

Comparative study between Isotretinoin Alone versus Isotretinoin Combined with Either Levocetirizine or Desloratadine in The Treatment of Acne Vulgaris [PDF]

International Journal of Medical Arts
Background: Many studies have proved isotretinoin's effectiveness in the treatment of acne. However, because of the potential for mucocutaneous side effects and acne outbreaks, it should be used and monitored with caution. To avoid undesired side effects,
Ebtihal Elsekily, Emad Elgmal, Hany Aboelwafa   +2 more
doaj   +1 more source

Isotretinoin Use in Transmasculine Patients and Its Implication on Chest Masculinization Surgery: Scoping Review of the Literature

JMIR Dermatology, 2023
BackgroundAcne often worsens in transmasculine patients who are on prolonged testosterone therapy. Isotretinoin is an oral retinoid used in the treatment of severe or refractory cases of acne, but it has the potential to cause ...
Daniel Strock, Torunn E Sivesind, Robert P Dellavalle, Gerhard S Mundinger   +3 more
doaj   +1 more source