Results 21 to 30 of about 1,037 (173)

Immunohistochemical Expression of Haptoglobin in Skin Lesions of Hidradenitis Suppurativa

Life
Background: Meta-inflammation is a hallmark of hidradenitis suppurativa (HS). Research on meta-inflammation in HS is growing, but there is still no research on haptoglobin as an inflammatory protein in lesional HS skin.
Nessr Abu Rached, Hanna Telkemeyer, Marina Skrygan, Martin Doerler, Yannik Haven, Lennart Ocker, Daniel Myszkowski, Thomas Meyer, Markus Stücker, Eggert Stockfleth, Falk G. Bechara   +10 more
doaj   +1 more source

The Impact of Surgery on Quality of Life in Hidradenitis Suppurativa: Results from a Prospective Single-Center Study

Life
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs quality of life. Treatment typically involves a patient-oriented combination of medical therapies, surgery, and lifestyle modifications.
Lennart Ocker, Nessr Abu Rached, Anna Koller, Carolin Frost, Riina Käpynen, Falk G. Bechara   +5 more
doaj   +1 more source

Reproductive Potential and Outcomes in Patients with Hidradenitis Suppurativa: Clinical Profile and Therapeutic Implications

Life, 2021
There are scarce data available regarding the impact of hidradenitis suppurativa (HS) on fertility, course and outcome of pregnancy and risk associated with treatments.
Trinidad Montero-Vilchez, Luis Salvador-Rodriguez, Andrea Rodriguez-Tejero, Manuel Sanchez-Diaz, Salvador Arias-Santiago, Alejandro Molina-Leyva   +5 more
doaj   +1 more source

A state-of-the-art systematic review of cancer in hidradenitis suppurativa

Annals of Medicine
Purpose Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with an increased risk of malignancy. The aim of this systematic review was to investigate the prevalence of different malignancies in HS.Methods This review meets the ...
Nessr Abu Rached, Jonas Rüth, Thilo Gambichler, Lennart Ocker, Falk G. Bechara   +4 more
doaj   +1 more source

Immunohistochemical Characterisation of the Interstitial Inflammatory Environment: T-Cell- and B-Cell-Dominant Subtypes of Hidradenitis Suppurativa

Dermatopathology
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a complex immune response. Given the considerable heterogeneity of the clinical phenotype of HS, this study aimed to analyse the immunohistochemical pattern of interstitial ...
Nessr Abu Rached, Stefanie Bruckmüller, Martin Doerler, Hanna Telkemeyer, Lennart Ocker, Yannik Haven, Daniel Myszkowski, Markus Stücker, Eggert Stockfleth, Falk G. Bechara   +9 more
doaj   +1 more source

Epidemiology of hidradenitis suppurativa in Poland in relation to international data

Przegląd Dermatologiczny, 2017
Hidradenitis suppurativa (acne inversa) is a chronic, inflammatory, recurrent, debilitating disease of hair follicles manifested by painful, deepseated, inflamed lesions localized in intertriginous areas.
Łukasz Matusiak, Andrzej Kaszuba, Dorota Krasowska, Waldemar Placek, Jacek Szepietowski   +4 more
doaj   +1 more source

Economic burden of hidradenitis suppurativa based on healthcare resource utilization: German claims data analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease affecting approximately 0.1% of the German population. Patients with HS require substantial healthcare resource utilization. This study aimed to assess the economic burden associated with HS in Germany.
Falk G. Bechara, Tanja Tran, Sandeep Kiri, Romy Bley, Kathrin Schlüter, Claudia Grellmann, Sima Melnik, Sylke Schneider‐Burrus   +7 more
wiley   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis, Erkan Alpsoy, Florian Anzengruber, Matthias Augustin, Falk G. Bechara, Pierre‐André Becherel, Farida Benhadou, Vincenzo Bettoli, Joana Cabete, Raffaele Dante Caposiena Caro, Antonella Di Cesare, Giovanni Damiani, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Krisztián Gáspár, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Barbara Horvath, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Alexander Katoulis, Natalia Kirsten, Georgios Kokolakis, Piotr K. Krajewski, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Andreas Pinter, Anna Pirogova, Maurizio Podda, Francesca Prignano, Jorge Romani, Marco Romanelli, Elia Rosi, Samed Sahin, Ditte M. L. Saunte, Sylke Schneider‐Burrus, Mariano Suppa, Jacek Szepietowski, Andrea Szegedi, Simon Francis Thomsen, Thrasyvoulos Tzellos, Anastasia Trigoni, Hessel H. Van Der Zee, Kelsey Van Straalen, Skaidra Valiukevičiene, Eva Vilarrasa, Esther von Stebut, Christos C. Zouboulis   +54 more
wiley   +1 more source

Long‐term efficacy of biologics in moderate‐to‐severe hidradenitis suppurativa: A systematic review and MAIC

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A matching‐adjusted indirect treatment comparison (MAIC) was conducted, comparing approved biologics for long‐term (48–52 weeks) treatment of moderate‐to‐severe hidradenitis suppurativa (HS). Using weighted patient‐level trial data allowed re‐estimation of relative bimekizumab efficacy compared with aggregate secukinumab and adalimumab trial data ...
Thrasyvoulos Tzellos, Vincent Piguet, Michael Frank Mørup, Leah Davis, Vanessa Taieb, Sandeep Kiri, Victoria Shodimu, Abby Paine, Brian Kirby, Haley B. Naik   +9 more
wiley   +1 more source

Hidradenitis suppurativa - current and promising non-surgical treatment

Journal of Education, Health and Sport, 2023
Introduction and purpose: Hidradenitis suppurativa (HS) also known as acne inversa is a chronic, inflammatory dermatosis with predilection to apocrine gland-rich regions.
Natalia Baran, Klaudia Bogusz, Marcela Maksymowicz, Adriana Bielak, Aleksandra Nowak, Łucja Cywka, Weronika Szwed, Alicja Nowak, Piotr Machowiec   +8 more
doaj   +1 more source