Results 31 to 40 of about 1,037 (173)

Addiction in chronic inflammatory skin diseases: A systematic review of prevalence, impact and screening practices

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review included 38 studies assessing substance‐related and behavioural addictions in patients with chronic inflammatory skin diseases. Nicotine and alcohol use were the most frequently reported addictive behaviours. Addictions were associated with increased disease severity, impaired treatment outcomes and greater psychosocial burden ...
Enya Müller, Stefanie Ziehfreund, Magdalena Saak, Sofia Besi, Kilian Eyerich, Alexander Zink   +5 more
wiley   +1 more source

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source

Measuring success in HS treatment from the physician's and the patient's perspective

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Integrated clinician (HiSCR, IHS4, IHS4‐55, HS‐IGA) and patient (HiSQOL, DLQI) scores, combined with imaging‐based fibrosis and inflammation assessment, redefine treatment success in hidradenitis suppurativa by aligning treat‐to‐target strategies with both inflammatory control and irreversible structural damage.
Georgios Nikolakis, Monika Arenbergerova, Zeljko Mijuskovic, Baoxi Wang, Christos C. Zouboulis   +4 more
wiley   +1 more source

Advances in the pharmacological treatments for acne inversa

Pifu-xingbing zhenliaoxue zazhi
Acne inversa, also known as hidradenitis suppurativa, is a refractory chronic inflammatory dermatosis. It is extremely painful in acute phase, while chronic, recurrent attacks can result in disfigurement.
SUN Yuanyuan, YANG Yuying, FU Wenjing
doaj   +1 more source

Digital Dermatology

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 7, Page e934-e952, July 2026.
SUMMARY Digital transformation is fundamentally reshaping dermatology, creating new opportunities in diagnostics, therapy, and healthcare organization. Large datasets combined with Artificial Intelligence (AI) enable more precise classification and prognosis, particularly through the analysis of clinical and dermoscopic imaging.
Lea Henkel, Avend Bamarni, Stephan Alexander Braun, Valentina Busik, Holger Andreas Haenssle, Stephan Rietz, Paul Schmidle, Sandra Schuh, Anna‐Theresa Seitz, Sebastian Sitaru, Stephan Traidl, Max Tischler, Felix von Krogh, Julia Welzel, Julia Winkler, Anastasia Sophie Vollmer, Katharina Susanne Kommoss, Alexander Zink   +17 more
wiley   +1 more source

Efficacy of Biologics for Hidradenitis Suppurativa: A Network Meta Analysis and Meta Regression for Baseline Disease Severity

Australasian Journal of Dermatology, Volume 67, Issue 3, Page e154-e161, May 2026.
ABSTRACT Hidradenitis Suppurativa is a challenging, heterogeneous inflammatory skin disease, with three approved biologic therapies. No head‐to‐head studies exist comparing these therapeutic modalities, and previous work has identified the influence of baseline disease severity upon clinical response.
James Pham, Tara Sholji, Marra Aghajani, Ericka Maye, Kate Burrell, Cindy Kok, John W. Frew   +6 more
wiley   +1 more source

In vitro and ex vivo immunomodulatory effects of human placental mesenchymal stem cells in hidradenitis suppurativa

Frontiers in Immunology
BackgroundHidradenitis suppurativa is a chronic inflammatory skin disease marked by immune dysregulation and elevated pro-inflammatory cytokines. While biologics like adalimumab target specific pathways, their limited efficacy highlights the need for ...
Vaiva Jariene, Vaiva Jariene, Paulius Valiukevicius, Paulius Valiukevicius, Ruta Insodaite, Ruta Insodaite, Ugne Janonyte, Romaldas Maciulaitis, Justinas Maciulaitis, Justinas Maciulaitis, Astra Vitkauskiene, Evelina Zemaite, Christos C. Zouboulis, Christos C. Zouboulis, Christos C. Zouboulis, Skaidra Valiukeviciene, Skaidra Valiukeviciene   +16 more
doaj   +1 more source

The Multifaceted Role of Keratinocytes in Hidradenitis Suppurativa Pathogenesis

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disorder of the pilosebaceous unit, with multiple factors contributing to its onset, activity and progression. Alongside a predisposing genetic background, hormonal and microbiome alterations, dysregulation of innate and adaptive immune response, as well as environmental ...
Chiara Moltrasio, Angelo Valerio Marzano, Maurizio Romagnuolo   +2 more
wiley   +1 more source

Introducing MCC-PS: a novel prognostic score for Merkel cell carcinoma

Frontiers in Oncology
IntroductionMerkel cell carcinoma (MCC) is an aggressive skin cancer with a poor prognosis, which only improved with the introduction of immunotherapies. An MCC prediction model with high diagnostic accuracy is lacking.
Nessr Abu Rached, Nessr Abu Rached, Jürgen C. Becker, Jürgen C. Becker, Anke S. Lonsdorf, Aric Keller, Ioannis A. Zeglis, Ioannis A. Zeglis, Thilo Gambichler, Thilo Gambichler, Thilo Gambichler   +10 more
doaj   +1 more source

Familial hidradenitis suppurativa is associated with an increased prevalence of metabolic and cardiovascular comorbidity

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Suzan Al‐Gburi, Niloofar Ghaffari, Michael Schultheis, Wolfram Jaschke, Florian Regensberger, Fiona André, Piotr K Krajewski, Alexandra Strobel, Petra Staubach, Katharina Hennig, Lukasz Matusiak, Simone Garcovich, Hans Bayer, Uwe Kirschner, Georgios Nikolakis, Jacek C Szepietowski, Matthias Schmuth, Esther von Stebut   +17 more
wiley   +1 more source