Results 51 to 60 of about 596 (172)

Advances in the pharmacological treatments for acne inversa

Pifu-xingbing zhenliaoxue zazhi
Acne inversa, also known as hidradenitis suppurativa, is a refractory chronic inflammatory dermatosis. It is extremely painful in acute phase, while chronic, recurrent attacks can result in disfigurement.
SUN Yuanyuan, YANG Yuying, FU Wenjing
doaj   +1 more source

Serum Proteomic Profiling Uncovers Dysregulated Keratinisation and Immune‐Related Pathways in Hidradenitis Suppurativa

Experimental Dermatology, Volume 35, Issue 4, April 2026.
ABSTRACT Hidradenitis suppurativa (HS) is an autoinflammatory keratinisation disease affecting the pilosebaceous unit and hallmarked by a complex and multifactorial pathogenesis. Although genomic and transcriptomic investigations have substantially advanced our understanding of key mechanisms underlying HS pathogenesis, proteomic studies remain limited,
Chiara Moltrasio, Sara Roncarà, Blendi Ura, Elena Maria Nardacchione, Eduardo Sommella, Ronald Moura, Federica Derlino, Angelo Valerio Marzano, Sergio Crovella, Paola Maura Tricarico   +9 more
wiley   +1 more source

Emotions and bodily experience in Hidradenitis Suppurative-Acne Inversa

, 2016
Hidradenitis Suppurative-Acne Inversa is one of the most debilitating chronic skin diseases. It seriously affects the emotional and relational life of the patient, it has a significant psychiatric comorbidity and it impairs the quality of life.We present
AGNOLI, Chiara, TUGNOLI, Stefano, CARACCIOLO, Stefano, BETTOLI, Vincenzo   +3 more
core   +1 more source

Two‐Stage Surgical Management of Anogenital Hidradenitis Suppurativa in Patients on Biologic Therapy: A Retrospective Case Series

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Hidradenitis suppurativa is a chronic inflammatory skin disorder causing painful nodules, abscesses and scarring, with the anogenital region presenting particular functional and reconstructive challenges. Although biologic therapy is commonly used in moderate to severe disease, its limitations highlight the role of surgery in advanced cases ...
Nino Fuchs, Lucija Pavljak, Dinko Hauptman, Marko Mance   +3 more
wiley   +1 more source

Towards the development of upgrade criteria for the treatment of hidradenitis suppurativa with biologics

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 4, Page 658-669, April 2026.
Forty‐three HS specialists from 22 European countries reported adherence to HS guidelines and use of antibiotics before biologics despite limited efficacy and rapid relapse (49% within 1–3 months). Seventy‐nine per cent supported short‐term biologics for severe Hurley I disease.
Georgios Nikolakis, Erkan Alpsoy, Monika Arenbergerova, Falk G. Bechara, Farida Benhadou, Joana Cabete, Raffaele Dante Caposiena Caro, Giovanni Damiani, Maia Delage Toriel, Veronique Del Marmol, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Evgeniya Hristakieva, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Niamh Kearney, Brian Kirby, Natalia Kirsten, Piotr K. Krajewski, Vesta Kucinskiene, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Francesca Prignano, Tadas Raudonis, Hans Christian Ring, Marco Romanelli, Samed Şahin, Ditte M. L. Saunte, Linnea Thorlacius, Thrasyvoulos Tzellos, Hessel H. Van Der Zee, Kelsey Van Straalen, Christos C. Zouboulis   +41 more
wiley   +1 more source

Pilonidal sinus disease: an intergluteal localization of hidradenitis suppurativa/acne inversa: a cross-sectional study among 2465 patients [PDF]

, 2019
Background: Hidradenitis suppurativa (HS), also referred to as acne inversa, is a debilitating skin disease characterized by inflammatory nodules, chronic abscesses and tunnels (fistulae and sinuses). The association with pilonidal sinus disease (PSD) is
Rigopoulos, D., Daxhelet, M., Iannone, M., von Laffert, M., Guillem, P., Danby, B., Romanelli, M., Kinyó, Á., Jemec, G.B.E., Benhadou, F., Zouboulis, C.C., del Marmol, V., Revuz, J., Theut Riis, P., Zisimou, C., Antoniou, C., Pascual, J.C., Puig, L., Van der Zee, H.H., Husein-ElAhmed, H., van van Straalen, K., Szepietowski, J.C., Wigny, K.M.G.J., Nikolakis, G., Mintoff, D., Dessinioti, C., Matusiak, L., Katoulis, A., Sinclair, R., Liakou, A.I., Alavi, A., Aquilina, S.   +31 more
core   +2 more sources

Introducing MCC-PS: a novel prognostic score for Merkel cell carcinoma

Frontiers in Oncology
IntroductionMerkel cell carcinoma (MCC) is an aggressive skin cancer with a poor prognosis, which only improved with the introduction of immunotherapies. An MCC prediction model with high diagnostic accuracy is lacking.
Nessr Abu Rached, Nessr Abu Rached, Jürgen C. Becker, Jürgen C. Becker, Anke S. Lonsdorf, Aric Keller, Ioannis A. Zeglis, Ioannis A. Zeglis, Thilo Gambichler, Thilo Gambichler, Thilo Gambichler   +10 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Scientometric evaluation of the global research in acne disease

, 2023
Background: Although acne is one of the most common diseases, medical literature lacks a scientometric analysis relevant to this disorder. In the present study we aimed to perform a scientometric evaluation of literature related to acne.
Senel, Engin, Khakimova, Aida, Zolotarev, Oleg   +2 more
core   +1 more source

In vitro and ex vivo immunomodulatory effects of human placental mesenchymal stem cells in hidradenitis suppurativa

Frontiers in Immunology
BackgroundHidradenitis suppurativa is a chronic inflammatory skin disease marked by immune dysregulation and elevated pro-inflammatory cytokines. While biologics like adalimumab target specific pathways, their limited efficacy highlights the need for ...
Vaiva Jariene, Vaiva Jariene, Paulius Valiukevicius, Paulius Valiukevicius, Ruta Insodaite, Ruta Insodaite, Ugne Janonyte, Romaldas Maciulaitis, Justinas Maciulaitis, Justinas Maciulaitis, Astra Vitkauskiene, Evelina Zemaite, Christos C. Zouboulis, Christos C. Zouboulis, Christos C. Zouboulis, Skaidra Valiukeviciene, Skaidra Valiukeviciene   +16 more
doaj   +1 more source