Results 71 to 80 of about 5,400 (237)

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

open access: yesInternational Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad   +2 more
wiley   +1 more source

THE TREATMENT OF ACNE SCARS

open access: yes, 2009
Acne scars represent a real challenge to the dermatologist: several histological and macroscopical distinctive features require different therapeutic approaches. Among the several available classification, Goodman et al.
FABBROCINI, GABRIELLA
core  

Assessing the Psychosocial Impact of Acne Scars on Individuals With Pigmented Skin: A Multicenter Observational Study

open access: yesDermatology Research and Practice
Acne scars, particularly in individuals with pigmented skin, can lead to significant psychosocial distress, yet the extent of this impact remains underexplored.
Marwa Majzoub   +2 more
doaj   +1 more source

Preliminary Validation of the Early Sacroiliitis Screening Tool (ESHST) for Identifying Hidradenitis Suppurativa Patients at High Risk of Spondyloarthritis

open access: yesInternational Journal of Dermatology, EarlyView.
Development and preliminary validation of the Early Sacroiliitis Screening Tool (ESHST), a dermatology‐oriented screening questionnaire for identifying hidradenitis suppurativa patients at increased risk of spondyloarthritis. ABSTRACT Background Hidradenitis suppurativa (HS) is increasingly recognized as a systemic inflammatory disease associated with ...
Umut Bakay   +3 more
wiley   +1 more source

Electrospun Biomaterials for Scarless Acne Wound Healing: Advances and Prospects

open access: yesJournal of Functional Biomaterials
Acne vulgaris is a chronic disease that occurs in the pilosebaceous units and ranks eighth in the global prevalence of all diseases. In its severe forms such as pustules, cysts, and nodules, acne can lead to permanent scarring and post-inflammatory ...
Jiahui Chen   +8 more
doaj   +1 more source

A combination approach to treating acne scars: Dot peeling, subcision, intradermal injection of PRP and microneedling [PDF]

open access: yesAl-Azhar International Medical Journal
Background: Inflammatory acne lesions can leave scars, which can affect a person's self-esteem and their ability to form healthy relationships. Chemical peels, microneedling, intradermal platelet-rich plasma, and subcision are just a few of the many ...
Amira Al-Khawaga, Asmaa Farag, Mona Ali
doaj   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis   +54 more
wiley   +1 more source

Assessment of life quality index among patients with acne vulgaris in a suburban population

open access: yesIndian Journal of Dermatology, 2016
Background and Aims: Acne vulgaris affects about 85% of adolescents, often extending into adulthood. Psychosocial impact of acne on health-related quality of life (QoL) has been identified, but it remains under-evaluated, especially in Indian patients ...
Neirita Hazarika, Radha K Rajaprabha
doaj   +1 more source

Long‐term efficacy of biologics in moderate‐to‐severe hidradenitis suppurativa: A systematic review and MAIC

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
A matching‐adjusted indirect treatment comparison (MAIC) was conducted, comparing approved biologics for long‐term (48–52 weeks) treatment of moderate‐to‐severe hidradenitis suppurativa (HS). Using weighted patient‐level trial data allowed re‐estimation of relative bimekizumab efficacy compared with aggregate secukinumab and adalimumab trial data ...
Thrasyvoulos Tzellos   +9 more
wiley   +1 more source

Management of Acne Scar uses Erbium Yag laser with ND-YAG laser [PDF]

open access: yes, 2017
Acne scars are making you self-conscious or embarrassed about your skin, learn about treatments that can remove or reduce their appearance. These acne scar treatments are not cure-alls, and insurance usually doesn’t cover them, but they do help to ...
Harlim, Ago
core  

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