Results 61 to 70 of about 5,422 (203)

Genomic and proteomic insights into hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou, Emmanouil Stylianakis, Isis Ricaño‐Ponce, Nick Keur, Theodora Kanni, Dimitra Stergianou, Mihai G. Netea, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis   +8 more
wiley   +1 more source

Assessing the Psychosocial Impact of Acne Scars on Individuals With Pigmented Skin: A Multicenter Observational Study

Dermatology Research and Practice
Acne scars, particularly in individuals with pigmented skin, can lead to significant psychosocial distress, yet the extent of this impact remains underexplored.
Marwa Majzoub, Eleonore Goubeau, Vivien Moris   +2 more
doaj   +1 more source

Cumulative isotretinoin dosing, treatment response and acne relapse: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this randomized controlled trial, cumulative isotretinoin doses of 120 and 150 mg/kg showed similar relapse rates at 12 months. Both regimens achieved substantial and comparable reductions in inflammatory acne lesions across the face, chest and back.
Ruggero Cascio Ingurgio, Angela Alfano, Antonio Costanzo, Julie S. Cronk, Rebecca Cummins, Benjamin S. Daniel, Ben J. Koszegi, Linda K. Martin, Clarisse G. Mendoza, Mae Ramirez‐Quizon, Lesley M. Rhodes, Heather I. Rishel, Adam I. Rubin, Fanny Satgé, Supriya Venugopal, Anna Wilson, Dedee F. Murrell   +16 more
wiley   +1 more source

Fractional Erbium-YAG Laser and Platelet-Rich Plasma as Single or Combined Treatment for Atrophic Acne Scars: A Randomized Clinical Trial

Dermatology and Therapy, 2019
Introduction Acne scarring is a common undesirable complication of acne vulgaris. Fractional erbium-yttrium aluminum garnet (YAG) 2940 nm laser and platelet-rich plasma have been used in treating acne scars with variable outcomes.
Moustafa A. El-Taieb, Hassan M. Ibrahim, Eisa M. Hegazy, Ahmed K. Ibrahim, Aya M. Gamal, Essam A. Nada   +5 more
doaj   +1 more source

Optimal treatment options for acne scars in patients with historic acne: a systematic review and network meta-analysis [PDF]

PeerJ
Background Acne is a common skin condition that can cause permanent scarring and profoundly affect patients’ quality of life. Despite the increasing diversity of acne scar treatments, there is a dearth of comprehensive evidence-based guidelines to help ...
Bingwei Wu, Mingju Gao, Yixuan Zhang, Xinping Bai   +3 more
doaj   +2 more sources

Measuring success in HS treatment from the physician's and the patient's perspective

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Integrated clinician (HiSCR, IHS4, IHS4‐55, HS‐IGA) and patient (HiSQOL, DLQI) scores, combined with imaging‐based fibrosis and inflammation assessment, redefine treatment success in hidradenitis suppurativa by aligning treat‐to‐target strategies with both inflammatory control and irreversible structural damage.
Georgios Nikolakis, Monika Arenbergerova, Zeljko Mijuskovic, Baoxi Wang, Christos C. Zouboulis   +4 more
wiley   +1 more source

Electrospun Biomaterials for Scarless Acne Wound Healing: Advances and Prospects

Journal of Functional Biomaterials
Acne vulgaris is a chronic disease that occurs in the pilosebaceous units and ranks eighth in the global prevalence of all diseases. In its severe forms such as pustules, cysts, and nodules, acne can lead to permanent scarring and post-inflammatory ...
Jiahui Chen, Liping Zhou, Zhongci Hang, Xiaochun Bian, Tong Huo, Bing Peng, Haohao Li, Yongqiang Wen, Hongwu Du   +8 more
doaj   +1 more source

5-Aminolevulinic Acid Photodynamic Therapy Combined with Intralesional Triamcinolone and 5-Fluorouracil to Treat Acne Hypertrophic Scar

Clinical, Cosmetic and Investigational Dermatology, 2023
Jingjing Wei, Lingyun Du, Zhiqiang Cao, Mingming Li, Chunhong Zhang, Chunmin Zhang, Liya Meng Department of Dermato-Venereology, The Second Hospital of Shandong University, Jinan, People’s Republic of ChinaCorrespondence: Liya Meng, Department of Dermato-
Wei J, Du L, Cao Z, Li M, Zhang C, Zhang C, Meng L   +6 more
doaj  

Consensus on energy‐based devices for keloids and hypertrophic scars: A Latin American Delphi study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Latin American Delphi consensus supports a sequential, multimodal approach to keloids and hypertrophic scars: vascular devices for early/inflammatory lesions; intralesional triamcinolone + 5‐fluorouracil and other injectable drugs for active scars; fractional lasers for texture; and pigment‐targeting therapies for dyschromia, prioritizing safety in ...
Gisele Viana de Oliveira, Patricia Apt Druck, Alvaro Andres Luque Acevedo, Doris Hexsel, Gabriel Teixeira Gontijo, Gabriel Huerta Rivera, Luis Leobardo Velázquez‐Arenas, Flávia Alvim Sant Anna Addor, Fátima Agüero Zaputovich, Hector Leal‐Silva, Sebastian Leal‐Delgado, Carlos Echevarría Escribens, Kleber Danilo Ollague Murillo, Susana Misticone, Leandra D'orsi Metsavaht, Johnny de la Riva, Daniel Ricardo Galimberti, Silvia Karina Kaminsky Jedwab, Hector Ricardo Galván Garcia, Marcia Ramos‐e‐Silva, Mariana Rocha Andrade, Eugenio Reis‐Filho, Marcio Roberto Silva, George Kroumpouzos, Daniela Guzmán‐Sánchez   +24 more
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source