Results 41 to 50 of about 5,400 (237)

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

Arthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D. Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Supplementary Material for: Clinical and Histological Effects of Topical Epidermal Growth Factor on Acne and Acne Scars

, 2022
Background: The inflammatory lesions of acne leave scars which greatly affect patients’ quality of life. Treatment options targeting both acne and acne scars are still lacking.
Choi S. (8336232), Cho S.I. (9550511), Kim J.W. (3231843), Suh D.H. (3835687), Yang J.H. (4130833), Yoon J.Y. (3835690), Kim D.H. (2862686)   +6 more
core   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

JEADV Clinical Practice, EarlyView.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro, Flaminia Antonelli, Dalma Malvaso, Federica Pellegrini, Elena Ippoliti, Niccolò Gori, Ketty Peris   +6 more
wiley   +1 more source

1726‐nm Laser Treatment of Hidradenitis Suppurativa Tunnels in a Pediatric Skin of Color Patient: Clinical and Ultrasound Outcomes

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To evaluate the safety, tolerability, and early clinical and ultrasound effects of a 1726‐nm laser for hidradenitis suppurativa (HS) tunnels in a pediatric patient with skin of color. Materials and Methods A 16‐year‐old female (Fitzpatrick skin type VI) with moderate HS and bilateral axillary draining tunnels underwent 4 monthly ...
Emilee M. Dreifus, Gabriela E. Beraja, Aditi Chokshi, Alyx Rosen, Ariel E. Eber   +4 more
wiley   +1 more source

Bio‐Based Microfluidics With Snail Slime: A By‐Product of Agriculture Plays an Exciting Role in the Chemistry of Microfluidic Reaction Chambers

Macromolecular Rapid Communications, EarlyView.
Due to a broad spectrum of active ingredients, snail slime presents a variety of exciting physical properties and chemical reactivities. Especially in the role of the reduction‐ and stabilizing agent for the manufacturing of gold nanoparticles, its great potential is revealed. Utilising the proteins found in slime, Nanoparticle‐comprising hydrogels are
Andrea Koball, Jens Gaitzsch
wiley   +1 more source

Atrophic scar formation in acne patients involves long-acting immune responses with plasma cells and alteration of sebaceous glands: Immune responses and sebaceous gland alteration in atrophic acne scar formation

, 2018
International audienceBACKGROUND:Possible outcomes of acne lesions are atrophic scars which may cause serious psychological distress. Current treatments of post-acne scarring often require invasive procedures.
Motte, M, V. Bourdes, P. Reiniche, M. Rivier, Dréno, Brigitte, P. Martel, S. Déret, Rivier, M, Fogel, P, Khammari, Amir, I. Carlavan, M. Motte, B. Bertino, P. Fogel, J.J. Voegel, C. Menigot, Déret, S, Menigot, C, A. Khammari, Bourdes, V, Carlavan, I, Bertino, B, Voegel, Johannes, J, Reiniche, P, B. Dreno, Martel, P   +25 more
core   +1 more source

Effectiveness of CO2 laser therapy in treating acne depressed scar: A protocol of systematic review

, 2020
Acne depressed scar (ADS) is a common type of facial skin disorder. It is estimated that the prevalence of postacne scar varies from 11% to 14% in the general population, and 49% of them affected with acne.
Huan Zang, Ya-nan Xu
core   +1 more source

Efficacy and Safety of Melaleuca alternifolia (Tea Tree) Oil for Acne—A Systematic Review and Meta‐Analysis

Phytotherapy Research, EarlyView.
ABSTRACT Acne vulgaris is a common chronic inflammatory skin disorder that begins in adolescents and often persists into adulthood, with substantial psychosocial impact. Tea tree oil (TTO) has been explored as a topical treatment for acne, but clinical evidence for its efficacy and safety remain limited and inconsistent. This systematic review and meta‐
Yixin Ye, Jun Jie Lim, Zongxun Huang, Fook Tim Chew   +3 more
wiley   +1 more source

Percutaneous Aponeurotomy and Lipofilling in Complex Periorbital Scar Revision

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Periorbital scars and deformities pose a significant challenge due to the region's delicate anatomy and esthetic importance. This case series explores the application of percutaneous aponeurotomy and lipofilling (PALF) in three patients with complex periorbital scarring resulting from surgical, traumatic, and pathological causes.
Daniel Karasik, Alexandra F. Welschmeyer, Eve Tranchito, Humzah Quereshy, Saikrishna Gourishetti, Cyrus C. Rabbani   +5 more
wiley   +1 more source