Results 11 to 20 of about 20,335 (199)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

From Damage to Functionality: Remanufacturing of Thrust Roller Bearings by Tailored Forming

Advanced Engineering Materials, EarlyView.
Herein, the wear and fatigue behavior of repaired bearing raceways with a new powder alloy is investigated using a FE8 test‐rig and an oscillating tribometer. The tests are compared with industrial manufactured bearings to evaluate the repair quality. The repair can extend the service life of the repaired bearing to that of a new bearing and improves ...
Felix Saure, Florian Pape, Gerhard Poll, Max Marian   +3 more
wiley   +1 more source

Mechanisms of De‐icing by Surface Rayleigh and Plate Lamb Acoustic Waves

Advanced Engineering Materials, EarlyView.
Ice accretion impacts daily life, renewable energy generation, maintenance, and security in industries and aeronautics. Acoustic waves (AW) are a promising method for ice removal, although de‐icing mechanisms require further investigation to optimize energy efficiency.
Shilpi Pandey, Jaime del Moral, Stefan Jacob, Laura Montes, Jorge Gil‐Rostra, Alejandro Frechilla, Atefeh Karimzadeh, Victor J. Rico, Raul Kanter, Niklas Kandelin, Carmen López‐Santos, Heli Koivuluoto, Luis Angurel, Andreas Winkler, Ana Borrás, Agustin R. González‐Elipe   +15 more
wiley   +1 more source

Advances in Hybrid Icing and Frosting Protection Strategies for Optics, Lens, and Photonics in Cold Environments Using Thin‐Film Acoustic Waves

Advanced Engineering Materials, EarlyView.
This article provides a comprehensive overview of fundamentals and recent advances of transparent thin‐film surface acoustic wave technologies on glass substrates for monitoring and prevention/elimination of fog, ice, and frost. Fogging, icing, or frosting on optical lenses, optics/photonics, windshields, vehicle/airplane windows, and solar panel ...
Hui Ling Ong, Zhangbin Ji, Luke Haworth, Yihao Guo, Jaime del Moral, Stefan Jacob, Ana Borras, Agustin R. Gonzalez‐Elipe, Jikai Zhang, Jian Zhou, Glen McHale, Yong‐Qing Fu   +11 more
wiley   +1 more source

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

Advanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani, Surabhi Nadigotti, Erfan Fatehi, Derek Aranguren van Egmond, Behnam Ashrafi   +4 more
wiley   +1 more source

On the Rigidity and Mechanical Behavior of Triply Periodic Minimal Surfaces‐Based Lattices: Insights from Extensive Experiments and Simulations

Advanced Engineering Materials, EarlyView.
This study examines the mechanical properties of triply periodic minimal surfaces (TPMS)‐based lattices, analyzing 36 architectures in elastic and plastic regimes. It evaluates the applicability of beam‐based scaling laws to TPMS lattices. Rigidity arises from the alignment of members with the load direction and solid regions preventing rotation.
Lucía Doyle, Humberto Terrones, Carlos González   +2 more
wiley   +1 more source

Quality Enhancement of Laser Powder‐Bed Fusion Parts by Acoustically Assisted Additive Manufacturing by Laser Powder‐Bed Fusion and its Application to Lattice Structures

Advanced Engineering Materials, EarlyView.
Additive manufacturing technologies like laser powder‐bed fusion offer great design freedom and individualization of products down to a batch size of one. However, parts fabricated with this technology suffer from poor quality. Acoustic assistance during the build process can minimize these drawbacks.
Oliver Maurer, Dirk Bähre
wiley   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Shape‐Reconfigurable Crack‐Based Strain Sensor with Ultrahigh and Tunable Sensitivity

Advanced Functional Materials, EarlyView.
A highly sensitive crack‐based sensor with tunable strain detection capabilities is demonstrated through controlled nanocrack formation in a line‐patterned shape memory polymer substrate. The sensor design integrates thermoplastic polyurethane and poly(lactic acid), enabling thermo‐responsive reconfiguration of crack geometry.
Seungjae Lee, Youngoh Lee, Cheolhong Park, Yun Goo Ro, Min Sub Kwak, Geonyoung Jeong, Junseo Park, Hyejin Lee, Pan Kyeom Kim, Sung‐Il Chung, Hyunhyub Ko   +10 more
wiley   +1 more source