Results 141 to 150 of about 6,664,068 (391)

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Clinical and molecular characteristics, therapeutic strategies, and prognosis of non-small cell lung cancer patients harboring primary and acquired BRAF mutations

Frontiers in Oncology
BackgroundThe differences in clinical characteristics and treatment prognosis in NSCLC patients harboring primary and acquired BRAF mutations are still poorly understood.MethodsFrom Oct 2017 to Dec 2023, 10, 211 lung cancer patients at Shanghai Ruijin ...
Xiangran Feng, Ran Zeng, Mengchen Lyu, Xiaoyan Chen, Ziwei Xu, Yue Hu, Zhiyao Bao, Zhiyao Bao, Zhiyao Bao, Xianwen Sun, Xianwen Sun, Xianwen Sun, Jingya Zhao, Jingya Zhao, Jingya Zhao, Ling Zhou, Ling Zhou, Ling Zhou, Jun Zhou, Jun Zhou, Jun Zhou, Beili Gao, Beili Gao, Beili Gao, Lei Dong, Yi Xiang, Yi Xiang, Yi Xiang   +27 more
doaj   +1 more source

Acquired Mucocele of Gall-bladder in Childhood [PDF]

, 1958
Robin Williams
openalex   +1 more source

Acquired EGFR C797S mediates resistance to AZD9291 in advanced non-small cell lung cancer harboring EGFR T790M

Nature Network Boston, 2015
Here we studied cell-free plasma DNA (cfDNA) collected from subjects with advanced lung cancer whose tumors had developed resistance to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) AZD9291.
K. Thress, C. Paweletz, E. Felip, B. Cho, Daniel B. Stetson, B. Dougherty, Z. Lai, A. Markovets, A. Vivancos, Y. Kuang, D. Ercan, Sarah E Matthews, M. Cantarini, J. Barrett, P. Jänne, G. Oxnard   +15 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

THE CHLOROFORM HABIT ACQUIRED BY A HYSTERICAL WOMAN RESULTING IN DEATH. [PDF]

, 1903
E. Percy Court
openalex   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

ARTHRODESIS OF SOME OF THE SMALLER JOINTS IN THE TREATMENT OF PARALYTIC AND ACQUIRED DEFORMITIES [PDF]

, 1912
ROBERT E. SOULE
openalex   +1 more source

Analyzing and Interpreting Neural Networks for NLP: A Report on the First BlackboxNLP Workshop

, 2019
The EMNLP 2018 workshop BlackboxNLP was dedicated to resources and techniques specifically developed for analyzing and understanding the inner-workings and representations acquired by neural models of language.
Alishahi, Afra, Chrupała, Grzegorz, Linzen, Tal   +2 more
core   +1 more source

Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

Frontiers in Microbiology, 2014
Polymyxins are polycationic antimicrobial peptides that are currently the last-resort antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections.
A. O. Olaitan, S. Morand, J. Rolain
semanticscholar   +1 more source