Results 1 to 10 of about 17,146 (159)

Case Report: Familial partial lipodystrophy, description of novel and ultrarare variants with distinct phenotypic spectrum [PDF]

Frontiers in Endocrinology
Familial partial lipodystrophy (FPLD) is a rare inherited disorder characterized by selective loss of subcutaneous fat and severe metabolic complications.
Silvia Magno, Caterina Pelosini, Melania Paoli, Donatella Gilio, Lavinia Palladino, Francesca Menconi, Andrea Barison, Giancarlo Todiere, Simona Ortori, Barbara Coco, Giordano Paolucci, Guido Salvetti, Maria Rita Sessa, Giovanni Ceccarini, Ferruccio Santini   +14 more
doaj   +2 more sources

The acromegaly lipodystrophy

Frontiers in Endocrinology, 2022
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj   +3 more sources

Lipodystrophy Syndromes [PDF]

Dermatologic Clinics, 2008
Lipodystrophy syndromes comprise a group of rare, heterogeneous disorders characterized by progressive loss of fat tissue, mainly from subcutaneous compartment and occasionally affecting visceral fat. Lipoatrophy may be partial, localized, or generalized.
Raúl De Lucas, Pedro Herranz
exaly   +4 more sources

Pathways to improving the awareness, diagnosis and management of lipodystrophy in Brazil: an expert panel discussion [PDF]

Diabetology & Metabolic Syndrome
Background Lipodystrophy syndromes are a group of rare, clinically complex disorders characterized by a partial or generalized lack of adipose tissue. Affected individuals develop severe metabolic comorbidities and frequently display absolute or relative
Josivan Gomes Lima, Cynthia Melissa Valerio, Amélio F. Godoy-Matos, Gerson Carvalho, Joana R. Dantas, João Eduardo Nunes Salles, Fernando Gerchman, Renan Montenegro Jr.   +7 more
doaj   +2 more sources

Lipodystrophy Syndromes

Endocrinology and Metabolism Clinics of North America, 2016
Lipodystrophies are heterogeneous disorders characterized by varying degrees of body fat loss and predisposition to insulin resistance and its metabolic complications. They are subclassified depending on degree of fat loss and whether the disorder is genetic or acquired. The two most common genetic varieties include congenital generalized lipodystrophy
Abhimanyu Garg
exaly   +4 more sources

Case Report: Metreleptin treatment enables successful pregnancy in a female with congenital generalized lipodystrophy [PDF]

Frontiers in Endocrinology
Lipodystrophy is a rare group of conditions characterized by partial or total absence of adipose tissue in the body. The lipodystrophy is either congenital or acquired and is also classified further to either generalized or partial.
Maria Somali, Emmanouil Korakas, Eirini Pizirtzidou, Zoe A. Efstathiadou, Michail Sapranidis, Zadalla Mouslech   +5 more
doaj   +2 more sources

Circulating Levels of MiRNAs From 320 Family in Subjects With Lipodystrophy: Disclosing Novel Signatures of the Disease

Frontiers in Endocrinology, 2022
Lipodystrophy (LD) indicates a group of rare disorders, with generalized or partial loss of white adipose tissue (WAT) often associated with metabolic derangements.
Alessia Dattilo, Alessia Dattilo, Giovanni Ceccarini, Gaia Scabia, Gaia Scabia, Silvia Magno, Lara Quintino, Caterina Pelosini, Guido Salvetti, Roberto Cusano, Matteo Massidda, Lucia Montanelli, Donatella Gilio, Gianluca Gatti, Alessandro Giacomina, Mario Costa, Mario Costa, Ferruccio Santini, Margherita Maffei, Margherita Maffei   +19 more
doaj   +1 more source

Lipodystrophies in Children [PDF]

Hormone Research in Paediatrics, 2022
<b><i>Background:</i></b> Lipodystrophy includes a wide group of diseases characterized by reduction, absence, or altered distribution of adipose tissue. Lipodystrophies are classified into generalized or partial, according to the fat distribution, and congenital or acquired, considering the etiology.
Francesca, Mainieri, Francesco, Chiarelli   +1 more
openaire   +2 more sources

Brachioplasty in ex-obese patients: proposed classification [PDF]

Revista Brasileira de Cirurgia Plástica, 2023
Introduction: Surgical treatment of morbid obesity has resulted in a greater demand for repairing procedures for sequelae caused by weight loss. Brachioplasty treats excess skin and localized lipodystrophy in the arm and armpit regions.
Rodrigo Pinto Gimenez, Erick Samuel Santos De Mello, Raphaela Silveira Amaral, Tatiani Cerioni Toth   +3 more
doaj   +1 more source

Risk factors for diabetic foot ulcers in metreleptin naïve patients with lipodystrophy

Clinical Diabetes and Endocrinology, 2021
Aim Patients with lipodystrophy are at high risk for chronic complications of diabetes. Recently, we have reported 18 diabetic foot ulcer episodes in 9 subjects with lipodystrophy.
O Saydam, B Ozgen Saydam, SC Adiyaman, M Sonmez Ince, MA Eren, FE Keskin, H Bilen, M Dagdeviren, S Kaya, G Akinci, A Balci, C Altay, F Bayraktar, EA Oral, B Akinci   +14 more
doaj   +1 more source