Results 31 to 40 of about 30,524 (205)

Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho [PDF]

, 2011
Article approval pendingLatest World Health Organization guidelines recommend shifting away from Stavudine (d4T)-based regimens due to severe side effects.
Bygrave, Helen, Cleary, Susan, Ford, Nathan, Gadot, Laurent, Goemaere, Eric, Hilderbrand, Katherine, Jouquet, Guillaume, Kranzer, Katharina, Lee, Janice, Makakole, Lipontso, Trivino, Laura, Vlahakis, Natalie   +11 more
core   +2 more sources

Lipodystrophies in Children [PDF]

Hormone Research in Paediatrics, 2022
<b><i>Background:</i></b> Lipodystrophy includes a wide group of diseases characterized by reduction, absence, or altered distribution of adipose tissue. Lipodystrophies are classified into generalized or partial, according to the fat distribution, and congenital or acquired, considering the etiology.
Francesca, Mainieri, Francesco, Chiarelli   +1 more
openaire   +2 more sources

Prevalence of Insulin Injection-induced Lipodystrophy and Associated Risk Factors in Children and Adolescents With Type 1 Diabetes Mellitus

Journal of Pediatrics Review, 2022
Background: Lipodystrophy is the most common complication of insulin injection that has not been studied yet in children with Type 1 Diabetes Mellitus (T1DM) in Isfahan.
Neda Mostofizadeh, Milad Najafi, Silva Hovsepian, Elham Hashemi Dehkordi, Nousin Rostampour, Mahin Hashemipour   +5 more
doaj  

Cytokine profile and clinical metabolic alterations in HIV-1 infected individuals with and without lipodistrophy

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
The extensive use of Highly Active Antiretroviral Therapy (HAART) has transformed HIV infection into a chronic condition. Thus, metabolic alterations including lipodystrophy and dyslipidemia have been associated with the use of such medications.
L. C. R. Pontes-Cardoso, L. R. Souza, M. T. S. Peraçoli, P. C. M. Pereira   +3 more
doaj   +1 more source

Isolated Congenital Lower Limb Lipoatrophy: A Case Report and Literature Review

Plastic and Reconstructive Surgery, Global Open, 2023
Summary:. Lipoatrophy and lipodystrophy can often be used interchangeably in the literature. However, there are some key differences. Inflammation plays a preliminary role in subcutaneous adipose tissue (SAT) loss in lipoatrophy, whereas lipodystrophy ...
Abdullah M. Alhusain, MBBS, Osama A. Alrodiman, MBBS, Faisal A. Alfaqeeh, MBBS, Sami I. Alissa, MBBS, SB-Plast   +3 more
doaj   +1 more source

Lipodystrophy defined by Fat Mass Ratio in HIV-infected patients is associated with a high prevalence of glucose disturbances and insulin resistance

BMC Infectious Diseases, 2012
Introduction Combined antiretroviral therapy (cART) in the treatment of HIV-1 infection has been associated with complications, including lipodystrophy, hyperlipidaemia, insulin resistance (IR) and diabetes.
Freitas Paula, Carvalho Davide, Santos Ana, Mesquita Joana, Matos Maria, Madureira Antonio, Martinez Esteban, Sarmento António, Medina José   +8 more
doaj   +1 more source

The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion. [PDF]

, 2017
Common genetic variants at the ARL15 locus are associated with plasma adiponectin, insulin and HDL cholesterol concentrations, obesity, and coronary atherosclerosis.
Alison Sleigh, Anna Stears, Claire Adams, Felicity Payne, Inês Barroso, Isabel Huang-Doran, Katherine Fawcett, Nuno Rocha, Robert K. Semple, Stephen O’Rahilly, Vladimir Saudek   +10 more
core   +3 more sources

Lipodystrophy among HIV-Infected Patients Attending Care and Treatment Clinics in Dar es Salaam

AIDS Research and Treatment, 2017
Background. HIV infection and long-term HAART use are associated with metabolic and morphological changes. We assessed prevalence, types, and risk factors associated with lipodystrophy among HIV-infected adults attending CTC in Dar es Salaam, Tanzania ...
Marina Njelekela, Rose Mpembeni, Alfa Muhihi, Nzovu Ulenga, Eric Aris, Deodatus Kakoko   +5 more
doaj   +1 more source

The common pathophysiologic threads between Asian Indian diabetic’s ‘Thin Fat Phenotype’ and partial lipodystrophy: the peripheral adipose tissue transcriptomic evidences

Adipocyte, 2020
T2D is a complex disease with poorly understood mechanisms. In Asian Indians, it is associated with “thin fat” phenotype which resembles with partial lipodystrophy. We hypothesized that disturbed expression of lipodystrophy genes might play a role in T2D
Aditya Saxena, Pradeep Tiwari, Nitin Wahi, Anshul Kumar, Sandeep Kumar Mathur   +4 more
doaj   +1 more source

The acromegaly lipodystrophy

Frontiers in Endocrinology, 2022
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
doaj   +1 more source