Results 11 to 20 of about 16,802 (177)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Risk factors for diabetic foot ulcers in metreleptin naïve patients with lipodystrophy
Clinical Diabetes and Endocrinology, 2021 Aim Patients with lipodystrophy are at high risk for chronic complications of diabetes. Recently, we have reported 18 diabetic foot ulcer episodes in 9 subjects with lipodystrophy.
O Saydam +14 more
doaj +1 more source
Genetics of Lipodystrophy [PDF]
Endocrinology and Metabolism Clinics of North America, 2017 Lipodystrophy disorders are characterized by selective loss of fat tissue with metabolic complications including insulin resistance, hypertriglyceridemia, and nonalcoholic liver disease. These complications can be life-threatening, affect quality of life, and result in increased health care costs.
Marissa, Lightbourne, Rebecca J, Brown
openaire +2 more sources
Magnetic resonance spectroscopy to assess hepatic steatosis in patients with lipodystrophy
The Turkish Journal of Gastroenterology, 2020 Background/Aims: Lipodystrophy is a rare metabolic disorder characterized by near total or partial lack of subcutaneous adipose tissue and associated with insulin resistance.
Canan Altay +15 more
doaj +1 more source
The impact of HIV-associated lipodystrophy on healthcare utilization and costs
AIDS Research and Therapy, 2008 Background HIV disease itself is associated with increased healthcare utilization and healthcare expenditures. HIV-infected persons with lipodystrophy have been shown to have poor self-perceptions of health.
Lee Daniel +4 more
doaj +1 more source
Prevalence and factors associated with lipodystrophy in AIDS patients
Revista da Sociedade Brasileira de Medicina Tropical, 2014 Introduction: The published literature shows an increased occurrence of adverse events, such as human immunodeficiency virus (HIV)-associated lipodystrophy syndrome, that are associated with the continuous use of antiretroviral therapy.
Lunara Basqueroto Della Justina +3 more
doaj +1 more source
Natural history and comorbidities of generalised and partial lipodystrophy syndromes in Spain
Frontiers in Endocrinology, 2023 The rarity of lipodystrophies implies that they are not well-known, leading to delays in diagnosis/misdiagnosis. The aim of this study was to assess the natural course and comorbidities of generalised and partial lipodystrophy in Spain to contribute to ...
Antía Fernández-Pombo +14 more
doaj +1 more source
Treatment Options for Lipodystrophy in Children
Frontiers in Endocrinology, 2022 Lipodystrophy includes a heterogeneous group of rare diseases characterized by different amounts of adipose tissue loss and several metabolic complications, including hypertriglyceridemia, steatohepatitis and particularly insulin resistance, that may ...
Francesca Mainieri +2 more
doaj +1 more source
European lipodystrophy registry: background and structure
Orphanet Journal of Rare Diseases, 2020 Background Lipodystrophy syndromes comprise a group of extremely rare and heterogeneous diseases characterized by a selective loss of adipose tissue in the absence of nutritional deprivation or catabolic state. Because of the rarity of each lipodystrophy
Julia von Schnurbein +24 more
doaj +1 more source
Dermatologic Clinics, 2008 Lipodystrophy syndromes comprise a group of rare, heterogeneous disorders characterized by progressive loss of fat tissue, mainly from subcutaneous compartment and occasionally affecting visceral fat. Lipoatrophy may be partial, localized, or generalized.
Herranz P +3 more
openaire +3 more sources