Results 1 to 10 of about 183,584 (309)
Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy
Cell Metabolism, 2019 The physiological role of leptin is thought to be a driving force to reduce food intake and increase energy expenditure. However, leptin therapies in the clinic have failed to effectively treat obesity, predominantly due to a phenomenon referred to as ...
Shangang Zhao, Zhenyan He, Zhuzhen Zhang
exaly +2 more sources
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
New England Journal of Medicine, 1996 R. Considine +10 more
exaly +2 more sources
Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency
New England Journal of Medicine, 1999 I Sadaf Farooqi +2 more
exaly +2 more sources
Leptin and Obesity: Role and Clinical Implication
Frontiers in Endocrinology, 2021 The peptide hormone leptin regulates food intake, body mass, and reproductive function and plays a role in fetal growth, proinflammatory immune responses, angiogenesis and lipolysis. Leptin is a product of the obese (ob) gene and, following synthesis and
M. Obradović +7 more
semanticscholar +1 more source
Leptin Regulates Bone Formation via the Sympathetic Nervous System
Cell, 2002 Florent Elefteriou, Gerard Karsenty
exaly +2 more sources
BMC Genomics, 2021 Background Brown adipose tissue (BAT) is specialized to dissipate energy in the form of heat. BAT-mediated heat production in rodents and humans is critical for effective temperature adaptation of newborns to the extrauterine environment immediately ...
Sujoy Ghosh +10 more
doaj +1 more source
Leptin-Activity Modulators and Their Potential Pharmaceutical Applications
Biomolecules, 2021 Leptin, a multifunctional hormone primarily, but not exclusively, secreted in adipose tissue, is implicated in a wide range of biological functions that control different processes, such as the regulation of body weight and energy expenditure ...
Marianna Greco +6 more
doaj +1 more source
Aquaculture Reports, 2022 In mammals, leptin is an endocrine hormone involved in the regulation of feeding and energy metabolism, and glucocorticoids were previously reported to induce leptin gene expression.
Aifen Yan +7 more
doaj +1 more source
A small genomic region containing several loci required for gastrulation in Drosophila. [PDF]
PLoS ONE, 2009 Genetic screens in Drosophila designed to search for loci involved in gastrulation have identified four regions of the genome that are required zygotically for the formation of the ventral furrow.
Sam J Mathew +2 more
doaj +1 more source
Human Pathology Reports, 2022 Context: Breast cancer is the most common cancer and the most common cause of death from cancer among women. Leptin is thought to play role in cell proliferation.
Irem Atalay Karacay +5 more
doaj +1 more source