Results 41 to 50 of about 242,212 (304)
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
The effect of metformin on biomarkers associated with breast cancer outcomes: a systematic review, meta-analysis, and dose–response of randomized clinical trials [PDF]
, 2020 Purpose: Breast cancer is a leading cause of cancer mortality in developed countries. We performed a meta-analysis of randomized clinical trials to investigate the effect of metformin on biomarkers associated with breast cancer outcomes and to explore ...
Chhabra, M. +9 more
core +2 more sources
Effects of methamphetamine on locomotor activity and thalamic gene expression in leptin-deficient obese mice [PDF]
, 2017 Leptin is an adipose-derived hormone that regulates energy balance. Leptin receptors are expressed in extrahypothalamic sites and several reports showed that leptin can influence feeding and locomotor behavior via direct actions on dopaminergic neurons ...
Bisagno, Veronica +3 more
core +2 more sources
Dexamethasone and Acetate Modulate Cytoplasmic Leptin in Bovine Preadipocytes [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 Hormonal and nutrient signals regulate leptin synthesis and secretion. In rodents, leptin is stored in cytosolic pools of adipocytes. However, not much information is available regarding the regulation of intracellular leptin in ruminants.
Shinichi Yonekura +5 more
doaj +1 more source
Journal of Lipid Research, 2006 The mechanisms of the increased serum leptin in response to feeding are poorly understood. Therefore, we used metabolic labeling to directly assess leptin biosynthesis, secretion, and turnover in adipose tissue from 14 h-starved compared with fed 12–14 ...
Mi-Jeong Lee, Susan K. Fried
doaj +1 more source
Longitudinal associations of leptin and adiponectin with heart rate variability in children [PDF]
, 2017 For early prevention of cardiovascular disease, early detection and risk factor insights are necessary. The autonomic balance reflects cardiovascular risk and can be measured by heart rate variability (HRV).
Michels, Nathalie, Van De Wielle, Roos
core +3 more sources
Establishment of Leptin-Responsive Cell Lines from Adult Mouse Hypothalamus. [PDF]
PLoS ONE, 2016 Leptin resistance is considered to be the primary cause of obesity. However, the cause of leptin resistance remains incompletely understood, and there is currently no cure for the leptin-resistant state.
Hiroshi Iwakura +6 more
doaj +1 more source
, 2006 Intracerebroventricular (ICV) administration of the hypothalamic neuropeptide neuromedin U (NMU) or the adipostat hormone leptin increases plasma ACTH and corticosterone.
Abbott, CR +11 more
core +1 more source
Effects of physical exercise on adiponectin, leptin, and inflammatory markers in childhood obesity: systematic review and meta-analysis [PDF]
, 2018 Background: New findings on adipose tissue physiology and obesity-Associated inflammation status suggest that modification of the adipokine level can be relevant for the long-Term prevention of obesity-Associated chronic disease. Objectives: The scope of
Bianco, Antonio +7 more
core +2 more sources
Frontiers in Endocrinology, 2017 The adipokine leptin regulates energy balance, appetite, and reproductive maturation. Leptin also acts on bone growth and remodeling, but both osteogenic and anti-osteogenic effects have been reported depending on experimental conditions.
Marie Kokolski +3 more
doaj +1 more source