Results 41 to 50 of about 186,310 (210)
PLoS Medicine, 2004 Background Sleep duration may be an important regulator of body weight and metabolism. An association between short habitual sleep time and increased body mass index (BMI) has been reported in large population samples.
S. Taheri +4 more
semanticscholar +1 more source
The Journal of Immunology, 2005 Abstract Leptin is an adipokine which conveys information on energy availability. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. As a cytokine, leptin also affects thymic homeostasis and, similar to other proinflammatory cytokines, leptin promotes Th1 ...
MATARESE, GIUSEPPE +2 more
openaire +6 more sources
Journal of Lipid Research, 2006 The mechanisms of the increased serum leptin in response to feeding are poorly understood. Therefore, we used metabolic labeling to directly assess leptin biosynthesis, secretion, and turnover in adipose tissue from 14 h-starved compared with fed 12–14 ...
Mi-Jeong Lee, Susan K. Fried
doaj +1 more source
Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]
PLoS ONE, 2016 Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams +5 more
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Role of leptin and leptin receptor in inflammation
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2003 on october 30th, 2002, the World Health Report by the World Health Organization was launched subtitled Reducing risks, promoting healthy life . Many of the health risks discussed in this report concern food consumption—either too little, in the case of the poor, or too much, in the case of ...
Halle, Martin, Persson, P. B.
openaire +3 more sources
Dexamethasone and Acetate Modulate Cytoplasmic Leptin in Bovine Preadipocytes [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 Hormonal and nutrient signals regulate leptin synthesis and secretion. In rodents, leptin is stored in cytosolic pools of adipocytes. However, not much information is available regarding the regulation of intracellular leptin in ruminants.
Shinichi Yonekura +5 more
doaj +1 more source
Tissue-specific effects of leptin on glucose and lipid metabolism.
Endocrine reviews, 2020 The discovery of leptin was intrinsically associated with its ability to regulate body weight. However, the effects of leptin are more far-reaching and include profound glucose-lowering and anti-lipogenic effects, independent of leptin's regulation of ...
S. Pereira +4 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2017 The adipokine leptin regulates energy balance, appetite, and reproductive maturation. Leptin also acts on bone growth and remodeling, but both osteogenic and anti-osteogenic effects have been reported depending on experimental conditions.
Marie Kokolski +3 more
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The Importance of Leptin to Reproduction.
Endocrinology, 2020 A healthy nutritional state is required for all aspects of reproduction and signaled by the adipokine leptin. Leptin acts in a relatively narrow concentration range; too much or too little will compromise fertility.
G. Childs +3 more
semanticscholar +1 more source
The Effects of Laparoscopic Sleeve Gastrectomy on the Parameters of Leptin Resistance in Obesity
Biomolecules, 2019 Obesity is a growing public health problem worldwide. Bariatric surgical procedures achieve the most sustainable and efficacious outcomes in the treatment of morbid obesity.
Tagleb S. Mazahreh +7 more
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