Results 51 to 60 of about 16,802 (177)

Dyslipidemia and nutritional status in patients HIV positive with Syndrome Lipodystrophy.

Revista de Epidemiologia e Controle de Infecção, 2014
Backgound and Objectives: Lipodystrophy in HIV is adversely affect the antiretroviral therapy (HAART), characterized by redistribution of body fat, as well as metabolic changes related to lipid profile, risk factor associated with increased ...
Isameriliam Rosaulem Pereira da Silva, Rosa Maria Dias, Andreza de Nazaré Leão Mendes, Rosana Maria Feio Libonati, Claudia Daniele Tavares Dutra   +4 more
doaj   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, Volume 34, Issue 7, Page 1420-1432, July 2026.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source

PROGRESSIVE LIPODYSTROPHY [PDF]

Archives of Internal Medicine, 1916
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openaire   +1 more source

Dysregulated Metabolism in People Living With HIV in the Modern ART‐Era: A Systematic Review of Targeted Metabolomics Studies

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia, Du Toit Loots, Shayne Mason, Esme Jansen Van Vuren, Monray E. Williams   +4 more
wiley   +1 more source

Impaired expression of mitochondrial and adipogenic genes in adipose tissue from a patient with acquired partial lipodystrophy (Barraquer-Simons syndrome): a case report

Journal of Medical Case Reports, 2008
Introduction Acquired partial lipodystrophy or Barraquer-Simons syndrome is a rare form of progressive lipodystrophy. The etiopathogenesis of adipose tissue atrophy in these patients is unknown.
Guallar Jordi P, Rojas-Garcia Ricardo, Garcia-Arumi Elena, Domingo Joan C, Gallardo Eduardo, Andreu Antoni L, Domingo Pere, Illa Isabel, Giralt Marta, Villarroya Francesc   +9 more
doaj   +1 more source

Fatty Pancreas and Risk of Type 2 Diabetes, Chronic Kidney Disease and Cardiovascular Events: Evidence From a Population‐Based Cohort

United European Gastroenterology Journal, Volume 14, Issue 6, July 2026.
ABSTRACT Background Fatty pancreas is a metabolically active ectopic fat depot, but its cardiometabolic implications have been assessed using heterogeneous thresholds. We investigated the association of fatty pancreas, quantified using MRI‐derived proton density fat fraction (PDFF) and categorised according to 2026 international consensus thresholds ...
Nicola Pugliese, Oveis Jamialahmadi, Arturo Cesaro, Valentina Flagiello, Rosellina M. Mancina, Alessio Aghemo, Stefano Romeo   +6 more
wiley   +1 more source

A muscular dystrophy associated with bi‐allelic LEMD2 variants: Expanding the genotype of nuclear envelopathies

Brain Pathology, Volume 36, Issue 4, July 2026.
Proteomics‐guided exome re‐analysis identifies bi‐allelic variants in the nuclear envelope LEMD2 gene, expanding its phenotypic spectrum. Created in BioRender. Pauper, M. (2026) https://BioRender.com/xamvo92.
Marc Pauper, Heike Kölbel, Iakowos Karakesisoglou, Anne Schänzer, Johann Böhm, Rachel Thompson, Nicolai Kohlschmidt, Bernd Ringel, Gisèle Bonne, Katja Neuhoff, Andrea Gangfuß, Ozge Aksel Kilicarslan, Sergi Beltran Agullo, Andreas Hentschel, Ulrike Schara‐Schmidt, Hanns Lochmüller, Kiran Polavarapu, Andreas Roos   +17 more
wiley   +1 more source

A qualitative assessment of patient journeys to a lipodystrophy diagnosis

Rare
Background: Lipodystrophy syndromes are a group of very rare disorders characterized by a deficiency of adipose tissue, that can present with a broad range of symptoms.
T. Kenny, S. Laird, S. Dunn, K. Iqbal
doaj   +1 more source

Congenital Generalized Lipoatrophy (Berardinelli-Seip Syndrome) Type 1: Description of Novel AGPAT2 Homozygous Variants Showing the Highly Heterogeneous Presentation of the Disease

Frontiers in Endocrinology, 2020
Berardinelli-Seip congenital lipoatrophy (BSCL) is characterized by near total fat atrophy, associated with the progressive development of metabolic complications. BSCL type 1 (BSCL1) is caused by mutations in AGPAT2, encoding 1-acylglycerol-3phosphate-O-
Giovanni Ceccarini, Silvia Magno, Caterina Pelosini, Caterina Pelosini, Federica Ferrari, Maria Rita Sessa, Gaia Scabia, Gaia Scabia, Margherita Maffei, Margherita Maffei, Isabelle Jéru, Isabelle Jéru, Olivier Lascols, Olivier Lascols, Corinne Vigouroux, Corinne Vigouroux, Corinne Vigouroux, Ferruccio Santini   +17 more
doaj   +1 more source