Results 171 to 180 of about 5,357,823 (357)

Eugenio Rignano upon the inheritance of acquired characters; [PDF]

open access: green, 1911
Eugenio Rignano   +1 more
openalex   +1 more source

To acquire or not to acquire: Mergers and Acquisitions in the Software Industry

open access: yes, 2018
The aim of this paper is to analyse the impact of Mergers and Acquisitions on firm growth for Software firms located in Catalonia. We investigate firms which are targeting, or are themselves the target of an acquisition and we find that the impact on is heterogeneous; there appear to be positive and negative impacts on productivity and ...
Méndez Ortega, Carles,   +1 more
openaire   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Acquired Reactive Perforating Collagenosis: Clinicopathologic Analysis of 12 Cases

open access: yesClinical, Cosmetic and Investigational Dermatology
Qiuli Zhang, Jianmin Chang Department of Dermatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s Republic of ChinaCorrespondence: Jianmin Chang, Department of ...
Zhang Q, Chang J
doaj  

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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