Results 201 to 210 of about 6,664,068 (391)

Enfermedad de von Willebrand adquirida. Aspectos generales Acquired von Willebrand’s disease. General aspects

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2004
La enfermedad de von Willebrand adquirida es una enfermedad hemorrágica poco común. Aproximadamente en la mitad de los casos se asocia con enfermedades linfoproliferativas y también se ha relacionado con trastornos mieloproliferativos, neoplasias ...
Alina Díaz Concepción
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Systemic Acquired Resistance

open access: yesPlant Signalling & Behavior, 2006
U. Conrath
semanticscholar   +1 more source

Acquired Resistance to Immune Checkpoint Inhibitors.

open access: yesCancer Cell, 2020
A. Schoenfeld, M. Hellmann
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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