Results 251 to 260 of about 6,664,068 (391)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Case Report: Clinical presentations of cyanosis associated with acquired methemoglobinemia in infants-a clinical challenge. [PDF]

Front Pediatr
Wang L, Ye Y, Li D, Li K, Yang P, Hu H, Liu X, Zhao Y.   +7 more
europepmc   +1 more source

Acquired Syphilis in Children [PDF]

, 1947
M. Murrell, M. S. Gray
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Acquired epidermodysplasia verruciformis secondary to methotrexate

JAAD Case Reports, 2023
Mohammed A. AlFada, MD, MBA, Ahmed A. AlHumidi, MD   +1 more
doaj  

Acute Intestinal Obstruction in Infancy and Childhood: Congenital Abnormalities: Acquired Causes: Treatment [PDF]

, 1927
Alastair H. MacLennan
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Physician mergers involve 38% of doctors, substantial health system participation, and frequent serial acquisition. [PDF]

Health Aff Sch
Deibler D, Hosken D, Koch T, Thomas M.
europepmc   +1 more source

Experimental Study of Acquired Resistance of the Rabbit's Renal Epithelium to Mercuric Chloride [PDF]

, 1929
Warren C. Hunter
openalex   +1 more source

Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors

Annals of Oncology, 2018
D. Westover, J. Zugazagoitia, B. Cho, C. Lovly, L. Paz-Ares   +4 more
semanticscholar   +1 more source