A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Microbiological diagnostic performance of metagenomic next-generation sequencing compared with conventional culture for patients with community-acquired pneumonia [PDF]
Tianlai Lin +11 more
openalex +1 more source
Microwave radiometric studies and ground truth measurements of the NASA/USGS Southern California test site [PDF]
The field measurement program conducted at the NASA/USGS Southern California Test Site is discussed. Ground truth data and multifrequency microwave brightness data were acquired by a mobile field laboratory operating in conjunction with airborne ...
Edgerton, A. T. +3 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Exploring the microbial landscape: uncovering the pathogens associated with community-acquired pneumonia in hospitalized patients [PDF]
Karin Hansen +7 more
openalex +1 more source
Building profile reconstruction using TerraSAR-X data time-series and tomographic techniques [PDF]
This work aims to show the potentialities of SAR Tomography (TomoSAR) techniques for the 3-D characterization (height, reflectivity, time stability) of built-up areas using data acquired by the satellite sensor TerraSAR-X.
Jean Marie, Nicolas +2 more
core
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
A Lifeboat for Failed Nasal Reconstructions: The Supraclavicular–Submental Sandwich Flap
Many failures in total or subtotal nasal reconstruction result from an underestimation of the amount of skin required for an adequate result, especially for sufficient lining. Such planning errors usually lead to poor results, with exposure of structural
Michel L.H.T. Vaena +3 more
doaj +1 more source
Acquired methemoglobinaemia is a relatively rare condition and, therefore infrequently encountered in acute medical practice. Suspicion of the condition may be triggered when the measured PaO2 is 'out of keeping' with the oxygen saturations that are discovered with pulse oximetry.
Adil Al-Lawati, Nick Murch
openaire +4 more sources
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer. [PDF]
Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance.
A Hübner +66 more
core +1 more source

