Results 111 to 120 of about 19,478 (225)
Schematic overview of the experimental workflow combining single‐cell RNA sequencing and spatial proteomics in a murine model of MASLD. Tissues were isolated, dissociated, and processed for single‐cell transcriptomic profiling to identify distinct cellular clusters and define cell‐type–specific gene expression signatures. Computational analysis enabled
Marica Meroni +18 more
wiley +1 more source
CDAHFD‐induced hepatic steatosis stimulates CBP/β‐catenin signaling in hepatocytes, leading to increased production of the downstream effector MMP‐7. Hepatocyte‐derived MMP‐7 contributes to fibrogenic responses and is associated with the progression of liver fibrosis.
Jun Imamura +5 more
wiley +1 more source
Acquired Hemophilia A successfully treated with rituximab
Acquired hemophilia A (AHA) is a rare bleeding disorder due to the development of specific autoantibodies against factor VIII. The anti-CD20 monoclonal antibody Rituximab has been proven to be effective in obtaining a long-term suppression of inhibitors
Giovanni D'Arena +4 more
doaj +1 more source
Acquired factor VIII inhibitor associated with chronic untreated hepatitis C
Acquired inhibitors of coagulation are antibodies that either inhibit the activity or increase the clearance of a clotting factor. A hemorrhagic diathesis is a common clinical manifestation in affected patients.
Abdussalam Shredi +3 more
doaj +1 more source
An overview in acquired hemophilia
This thesis focused on acquired hemophilia A, a rare coagulation disorder that equally affects males and females. However, there are two different peaks of incidence: in older age and, in the case of young women, during pregnancy/puerperium. This thesis analyzed, in particular, diagnostic difficulties and the main treatments currently available to ...
openaire +2 more sources
Pseudomonas aeruginosa bacteremia in patients undergoing liver transplantation: An emerging problem [PDF]
In our institution, Pseudomonas aeruginosa bacteremia appeared to occur with increasing frequency in patients undergoing liver transplantation. We thus conducted a prospective study to define risk factors and outcome in these patients.
Korvick, JA +3 more
core
CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome. [PDF]
Multiple genome-wide studies have identified associations between outcome of human immunodeficiency virus (HIV) infection and polymorphisms in and around the gene encoding the HIV co-receptor CCR5, but the functional basis for the strongest of these ...
Anderson, Stephen K +30 more
core

