Results 91 to 100 of about 19,249 (228)
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]
As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel +11 more
core +1 more source
ABSTRACT Background In the earlier PROTECT VIII Kids study (NCT01775618), damoctocog alfa pegol was efficacious for prevention and treatment of bleeds in children aged < 12 years with severe haemophilia A. Objective Assess the safety of damoctocog alfa pegol, including hypersensitivity and loss of efficacy (LoE) due to an immune response to ...
Margareth C. Ozelo +13 more
wiley +1 more source
Coexistence of Acquired Hemophilia and Antiphospholipid Serology in Monoclonal Gammopathy Patient
Nabil Belfeki, Sarra Hamrouni, Alessio Strazzulla, Sylvain Diamantis Department of Internal Medicine, Groupe Hospitalier Sud-Ile de France, Melun, 77000, FranceCorrespondence: Nabil BelfekiDepartment of Internal Medicine, Groupe Hospitalier Sud Ile de ...
Belfeki N +3 more
doaj
Schematic overview of the experimental workflow combining single‐cell RNA sequencing and spatial proteomics in a murine model of MASLD. Tissues were isolated, dissociated, and processed for single‐cell transcriptomic profiling to identify distinct cellular clusters and define cell‐type–specific gene expression signatures. Computational analysis enabled
Marica Meroni +18 more
wiley +1 more source
CDAHFD‐induced hepatic steatosis stimulates CBP/β‐catenin signaling in hepatocytes, leading to increased production of the downstream effector MMP‐7. Hepatocyte‐derived MMP‐7 contributes to fibrogenic responses and is associated with the progression of liver fibrosis.
Jun Imamura +5 more
wiley +1 more source
Acquired factor VIII inhibitor associated with chronic untreated hepatitis C
Acquired inhibitors of coagulation are antibodies that either inhibit the activity or increase the clearance of a clotting factor. A hemorrhagic diathesis is a common clinical manifestation in affected patients.
Abdussalam Shredi +3 more
doaj +1 more source
Advanced magnetic resonance imaging of cartilage components in haemophilic joints reveals that cartilage hemosiderin correlates with joint deterioration. [PDF]
IntroductionEvidence suggests that toxic iron is involved in haemophilic joint destruction.AimTo determine whether joint iron deposition is linked to clinical and imaging outcomes in order to optimize management of haemophilic joint disease.MethodsAdults
Barnes, Richard FW +7 more
core +2 more sources
Acute Atraumatic Compartment Syndrome of the Hand Due to Acquired Hemophilia A
Acquired hemophilia A (factor VIII inhibitor) is a rare idiopathic disease with a high rate of morbidity and mortality. We report the case of an 83-year-old woman who presented with atraumatic compartment syndrome of the right hand resulting from ...
Daniel Walder, MD +4 more
doaj +1 more source

