Results 111 to 120 of about 118,635,816 (237)

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Spontaneous Ecchymosis as Initial Presentation of Acquired Hemophilia A

Annals of Internal Medicine: Clinical Cases
Hemophilia A, a deficiency of clotting factor VIII, can be congenital, presenting with joint bleeding in childhood, or acquired, a rare subtype presenting as spontaneous bleeding most commonly seen in older adult patients.
Lahari Ramagiri, Anna L. Farrell, Julie Kielt   +2 more
doaj   +1 more source

Testing for Non‐Severe Heritable Platelet Function Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley, Naomi Cornish, Maria Molina Carretero, Sarah K. Westbury   +3 more
wiley   +1 more source

TREATMENT OF BLEEDING AND FACTOR VIII INHIBITORS IN ACQUIRED HEMOPHILIA A PATIENTS

Zdravniški Vestnik, 2004
Background. Bleeding in acquired hemophilia A patients with FVIII autoantibodies is often severe. The authors describe a successfuly acquired hemophilia A treatment with Feiba, glucocorticoids and cyclophosphamide in three patients.Results.
Peter Černelč, Janez Tomažič
doaj  

Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy

Journal of Small Animal Practice, EarlyView.
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth, S. M. DeMonaco, B. J. Conner, P. B. S. Serpa, A. R. Wilkinson   +4 more
wiley   +1 more source

Concurrent congenital hemophilia B and acquired hemophilia A: a unique case report

Congenital hemophilia B is a rare X-linked recessive bleeding disorder caused by factor IX deficiency. Acquired hemophilia A is a rare, acquired bleeding disorder that presents with new-onset bleeding, especially in older adults, due to the development ...
Cirik, Salih, Bicim, Soykan, Berber, Ilhami, Kaya, Emin, Erkurt, Mehmet Ali, Hidayet, Emine, Kuku, Irfan   +6 more
core   +1 more source

ACQUIRED HEMOPHILIA A IN 3 YEARS OLD CHILD IN LAMPUNG ETHNIC GROUP [PDF]

, 2014
Acquired Hemophilia A is extremely rare in children. It is about 1:1,000,000 cases per year. Although it is rare, it can cause fatal condition to death. A boy, 3 years old, had a complaint of bruising on the face and extremities, the swelling often occur
Astrini, Nabila Putri
core  

Acquired hemophilia of unknown etiology in an elderly man:Case report

, 2018
Objective: Unknown ethiology Background: Acquired hemophilia is a rare but potentially dangerous bleeding disorder caused by autoantibodies against coagulation factors. It affects 1 to 1.5 per 1 million people each year.
Lim, Soo Min, Loong, Joel Lee Xiang, Hoong, Chan Kwok, Botross, Nevein Philip, Stephen, Sonia Elvina   +4 more
core   +1 more source

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source

Inhibitors against spontaneously acquired coagulation factors: Acquired hemophilia B [PDF]

, 2003
Los inhibidores adquiridos del factor IX son extremadamente raros. Un hombre de 70 años presentó sangrado profuso continuo luego de una cirugía ortopédica. Su PTT activado inicial fue 77.4 segundos (intervalo normal, 25-36) y su PT fue normal.
Sossa Melo, Claudia Lucía, Rodríguez, Pilar, Jiménez Sanguino, Sara Inés   +2 more
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