Results 91 to 100 of about 118,635,816 (237)

Patient Perspectives in Haemophilia A: Unmet Needs of Individuals Receiving Factor and Non‐Factor Treatments

Haemophilia, EarlyView.
ABSTRACT Introduction There is limited qualitative published real‐world data on treatment patterns among people with severe haemophilia A (PwSHA), particularly those with unmet needs. Aim This qualitative study aimed to explore the impact of taking prophylactic extended half‐life factor VIII (EHL‐FVIII) or emicizumab on psychosocial and physical ...
Nana Kragh, Veruska Carboni, Duygu Bozkaya, Idaira Rodriguez‐Santana, Claudia Mighiu, Bethany Franks, Arnoud Plat, Randall Curtis   +7 more
wiley   +1 more source

Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A. [PDF]

, 2012
nefficient intracellular protein trafficking is a critical issue in the pathogenesis of a variety of diseases and in recombinant protein production.
Tonn, Torsten, Milanov, Peter, Schüttrumpf, Jörg, Seifried, Erhard, Patricia Quade-Lyssy, Quade-Lyssy, Patricia, Jörg Schüttrumpf, Roth, Stefanie D., Simpson, Jeremy C., Christopher Ungerer, Erhard Seifried, Abriss, Daniela, Pepperkok, Rainer, Rainer Pepperkok, Stefanie D Roth, Jeremy C Simpson, Torsten Tonn, Ungerer, Christopher, Peter Milanov, Daniela Abriss, Ungerer Christopher, Seifried Erhard, Abriss Daniela, Simpson Jeremy C., Quade-Lyssy Patricia, Milanov Peter, Schüttrumpf Jörg, Roth Stefanie D., Pepperkok Rainer, Tonn Torsten   +29 more
core   +1 more source

Expert Consensus on Assessment for Rehabilitation and Treatment of Musculoskeletal Complications of Hemophilia in China

, 2022
Hemophilia is a group of hereditary hemorrhagic diseases. Hemorrhages mostly occur in musculoskeletal system and is the main cause for disability. Rehabilitation plays an important role in the comprehensive management in hemophilia.
Hemophilia Treatment Center Collaborative Network of China, China Alliance for Rare Diseases, Hemophilia Subcommittee   +1 more
core   +1 more source

A Common Language for the Multidisciplinary Team: Point‐of‐Care Musculoskeletal Ultrasound in Modern Haemophilia Care

Haemophilia, EarlyView.
ABSTRACT The evolving haemophilia care landscape has evolved with personalised prophylaxis, new coagulation factor molecules, non‐replacement therapies, and gene therapy, leading to significantly reduced bleeding frequency and haemophilic arthropathy burden.
Hortensia De la Corte‐Rodriguez, María Teresa Álvarez‐Román, Mauro Davoli, Magnus Aspdahl, Christina Burgess, Karin Fijinvandraat, Roberta Gualtierotti, Cedric Hermans, Marko Marinić, Carlo Martinoli, Wolfgang Miesbach, Gianluigi Pasta, Michael Sigl‐Kraetzig, David Stephensen, Malin Svennefalk, Víctor Jiménez‐Yuste, the E.A.H.A.D. Joint Health Group   +16 more
wiley   +1 more source

Hemophilia & Acquired Hemophilia A Hemophilia & Acquired Hemophilia A

, 2020
Hemophilia is a ...
Tirunagari S, Dr Sreedhar Tirunagari, Shaik D   +2 more
core  

Hemofilia A adquirida Acquired hemophilia A

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010
La hemofilia A adquirida (HAA) es un trastorno hemorrágico poco frecuente caracterizado por la presencia de autoanticuerpos contra el factor VIII (FVIII) circulante.
Delfina Almagro Vázquez
doaj  

Acquired Factor VIII Inhibitors: Three Cases

Turkish Journal of Hematology, 2013
Acquired hemophilia A is a rare, but devastating bleeding disorder caused by spontaneous development of autoantibodies directed against coagulation factor VIII.
Tay Za Kyaw, S. Jayaranee, Ping Chong Bee, Edmund Fui Min Chin   +3 more
doaj   +1 more source

Understanding Contact Risks of Pediatric Physical Activity: Video Analysis to Inform Decisions for Children at Risk of Bleeding Injuries

Haemophilia, EarlyView.
ABSTRACT Introduction Physical activity guidelines for children with inherited or acquired bleeding disorders are largely based on expert opinion rather than objective measures of injury exposure, making evidence‐based participation recommendations challenging.
Lauren Backstein, Ria Patel, Mona Elmikaty, Brooklyn Westlake, Sarah Sbeiti, Leonardo R. Brandão, Robert Klaassen, Allison Clouthier, Chris Joslin, Ryan Graham, Patricia E. Longmuir   +10 more
wiley   +1 more source

Acquired Hemophilia Presenting as Gross Hematuria and Perineal Subcutaneous Hemorrhage after Prostate Biopsy : A Case Report [PDF]

, 2013
Acquired hemophilia is a rare disease that can result in life threatening bleeding associated with coagulation factor VIII inhibitors. A 61-year-old man presented gross hematuria and urinary retention.
木村, 博子, 植垣, 正幸, 橋村, 孝幸, 三好, 隆史, 青山, 輝義, 永井, 謙一   +5 more
core  

Population Pharmacokinetics of Plasma‑Derived Factor X Using Clotting and Chromogenic Assays: A WAPPS‑Hemo Model

Haemophilia, EarlyView.
ABSTRACT Background Hereditary factor X (FX) deficiency is a rare autosomal recessive bleeding disorder for which individualized pharmacokinetic (PK) assessment can support optimized prophylactic management. The WAPPS‐Hemo platform enables population pharmacokinetic (PopPK) individualized PK predictions based on sparse sampling.
Dagmar M. Hajducek, Pierre Chelle, Manuela Scarpellini, Andrea Edginton, Alfonso Iorio   +4 more
wiley   +1 more source