Results 11 to 20 of about 19,249 (228)
Acquired Hemophilia A with Gastrointestinal Bleeding [PDF]
Clinical Endoscopy, 2020 Peptic ulcer disease is the most common cause of acute gastrointestinal bleeding, followed by variceal bleeding, Mallory–Weiss syndrome, and malignancy.
Narae Park, Jin Seok Jang, Jae Hwang Cha
doaj +4 more sources
Acquired Hemophilia A and urothelial carcinoma [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2021 Acquired Hemophilia A (AHA) is a rare entity, resulting from the production of autoantibodies against Factor VIII of the coagulation cascade. These autoantibodies may develop in response to autoimmune conditions, drugs, neoplastic diseases, and pregnancy.
Fadi Taza +3 more
doaj +3 more sources
Acquired Hemophilia A successfully treated with rituximab [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2015 Acquired hemophilia A (AHA) is a rare bleeding disorder due to the development of specific autoantibodies against factor VIII. The anti-CD20 monoclonal antibody Rituximab has been proven to be effective in obtaining a long-term suppression of inhibitors
Giovanni D'Arena +4 more
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Acquired hemophilia A: A case report
Journal of Applied Hematology, 2017 Acquired hemophilia A is a rare autoimmune disorder where autoantibodies are produced against factor VIII. Its reported incidence is as low as 1.20 to 1.48 cases per million per years.
Sarita Pradhan, Adya Kinkar Panda
doaj +2 more sources
Acquired hemophilia A: emerging treatment options
Journal of Blood Medicine, 2015 Maissaa Janbain,1 Cindy A Leissinger,1 Rebecca Kruse-Jarres2 1Louisiana Center for Bleeding and Clotting Disorders, Tulane University Medical Center, New Orleans, LA, USA; 2Washington Center for Bleeding Disorders, Blood Works NW, Seattle, WA, USA ...
Janbain M, Leissinger CA, Kruse-Jarres R
doaj +5 more sources
Acquired Hemophilia A Presenting as Intramuscular Hematoma [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2018 Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma
Ghassan Al-Shbool MD, Anusha Vakiti MD
doaj +3 more sources
Baylor University Medical Center Proceedings, 2019 Acquired inhibitors of coagulation are a group of rare but potentially life-threatening blood disorders characterized by the presence of autoantibodies directed against clotting factor. Autoantibody against factor VIII is the most common form of clotting factor inhibitor, a condition also known as acquired hemophilia A.
Yadav, Pandey +4 more
+7 more sources
Tenri Medical Bulletin, 2013 Acquired hemophilia A (AHA) is a rare bleeding disorder caused by the autoantibody directed against factor VIII in patients without previous history of a bleeding disorder. We retrospectively analyzed the characteristics and outcomes of 49 patients with AHA diagnosed in our center from February 1994 to October 2012.
Yoshitomo Maesako +2 more
openaire +4 more sources
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Journal of Medical Case Reports, 2021 Background Acquired hemophilia A is a rare coagulopathy caused by inhibitors of blood coagulation factor VIII. Patients with acquired hemophilia A have a higher mortality risk (5–10%) than those with congenital hemophilia.
Keigo Maeda +3 more
doaj +1 more source