Results 41 to 50 of about 118,635,816 (237)
An overview in acquired hemophilia
, 2023 This thesis focused on acquired hemophilia A, a rare coagulation disorder that equally affects males and females. However, there are two different peaks of incidence: in older age and, in the case of young women, during pregnancy/puerperium. This thesis analyzed, in particular, diagnostic difficulties and the main treatments currently available to ...
openaire +2 more sources
Acquired hemophilia A: A case report
Journal of Applied Hematology, 2017 Acquired hemophilia A is a rare autoimmune disorder where autoantibodies are produced against factor VIII. Its reported incidence is as low as 1.20 to 1.48 cases per million per years.
Sarita Pradhan, Adya Kinkar Panda
doaj +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is a life‐threatening thrombotic microangiopathy characterized by acute neurological manifestations and long‐term sequelae related to microvascular brain injury. Cerebral small vessel disease (cSVD), detectable on MRI through lacunes, microbleeds, white matter hyperintensities, and ...
Addolorata Truma +13 more
wiley +1 more source
HemaSphere, 2021 Acquired hemophilia A and acquired von Willebrand syndrome are rare, but life-threatening bleeding disorders that require prompt diagnosis and treatment by hematologists.
Frank W. G. Leebeek
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Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Acquired Hemophilia A After SARS-CoV-2 Infection: A Case Report [PDF]
, 2022 Acquired hemophilia A is a rare autoimmune coagulation disorder associated to the development of neutralizing antibodies directed towards coagulation factor VIII, known as factor VIII inhibitors, in subjects with previous normal clotting system ...
Sabba C. +20 more
core +1 more source
Acquired hemophilia in patient with Systemic lupus erythematosus: Clinical case report
Научно-практическая ревматологияAcquired hemophilia is a rare disease that develops because of the synthesis of antibodies to endogenous VIII blood clotting factor. The most common symptom of acquired hemophilia is spontaneous bleeding.
S. A. Alekseeva +2 more
doaj +1 more source
Acquired hemophilia A (AHA): underreported, underdiagnosed, undertreated medical condition
The Egyptian Journal of Internal Medicine, 2022 Background Acquired hemophilia A (AHA) is a rare acquired bleeding disorder occurred due to the formation of inhibitory antibodies neutralizing endogenous factor VIII. Main body About half the cases are idiopathic.
Doaa M. El Demerdash +2 more
doaj +1 more source
Acquired Hemophilia A: A Rare, Acquired Coagulopathy in the Postpartum Setting
American Journal of Perinatology Reports, 2023 Postpartum hemorrhage (PPH) remains a leading cause of maternal morbidity. Pregnancy-associated acquired hemophilia A (AHA) caused by autoantibodies against factor VIII can present with recurrent episodes of postpartum bleeding.
Austin Oberlin +10 more
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International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective This study explores the barriers to the use of tranexamic acid (TXA) for the management of postpartum hemorrhage (PPH) and provides recommendations to improve its use. Methods We conducted a mixed‐methods assessment involving 229 healthcare professionals in Kano, Lagos, and Niger States of Nigeria.
Chukwunonso Nwaokorie +5 more
wiley +1 more source