Results 61 to 70 of about 118,635,816 (237)
Clinical Oral Implants Research, EarlyView.ABSTRACT Objective To compare ⌀3.3 mm and ⌀4.1 mm hydrophilic titanium‐zirconium implants supporting fixed dental prostheses (FDPs) in mandibular distal‐extension situations among participants with varying degrees of hyperglycaemia. Materials and Methods Participants were stratified according to HbA1c (5.8%–< 7.0% vs.
Supriya Ebenezer +4 more
wiley +1 more source
Postpartum Acquired Hemophilia A
Journal of Community Hospital Internal Medicine PerspectivesAcquired hemophilia A (AHA) is a bleeding disorder that occurs from aberrant production of autoantibodies that target factor VIII. The underlying cause of AHA is unclear but can present postpartum. Very few cases have reported instances of AHA coexisting with other hematological disorders, such as sickle cell trait (SCT).
Omar, Khawaja O. +2 more
openaire +2 more sources
Hematology & Transfusion International Journal, 2017 Acquired hemophilia A AHA is a rare but potentially life threatening bleeding disorder caused by the development of auto antibodies against circulating factor VIII Age distribution is bimodal with a first peak occurring among young women in postpartum period and a second major peak among elderly patients Fifty percent of cases are idiopathic ...
openaire +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Introduction Central venous catheter (CVC) insertion is frequently required in patients with haematological diseases. Despite limited evidence, thrombocytopenia often prompts prophylactic platelet transfusion before catheterisation. Methods We conducted an observational before‐and‐after study including the first non‐tunnelled CVC insertion ...
Mathias Lazarevic Lindblad +8 more
wiley +1 more source
Two Cases of Acquired Hemophilia A Successfully Treated with Oral Steroid or Danazol [PDF]
, 2017 Acquired Hemophilia A is a rare and considerably life-threatening coagulopathy, which is caused by the development of autoantibodies against factor VIII (FVIII) in non-hemophilic adults. Acquired FVIII inhibitors can be associated with diverse conditions,
박인혜 +7 more
core +1 more source
Acquired Hemophilia during Pregnancy and Postpartum [PDF]
Hemophilia is a genetic disease that affects blood coagulation. Acquired hemophilia A is an autoimmune-mediated bleeding disorder in which antibodies against coagulation factor VIII develop.
Ruiz Reyes, Dionis +4 more
core +1 more source
FVIIIa Mimetics: New Approaches and Next‐Generation Initiatives
Haemophilia, EarlyView.ABSTRACT Emicizumab has revolutionized hemophilia A care, yet limitations regarding the “ceiling” of hemostatic efficacy (equivalent to mild hemophilia) and global access persist. This review critically examines two distinct paradigms shaping the future of care: Innovation and Access. Regarding innovation, we synthesize the latest clinical data on next‐
Tadashi Matsushita +2 more
wiley +1 more source
Whole genome sequencing of Sars-COV-2 from Covid-19 acquired hemophilia patient
, 2022 Acquired hemophilia is an atypical pathology of SARS-CoV-2 infection, which could be variant associated. Here, we share a sequence of SARS-CoV-2 genome from patient with Covid-19 acquired hemophilia.
Kamarudin, Norhidayah +6 more
core
Gene Editing for Haemophilia—The Next Frontier
Haemophilia, EarlyView.ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti +3 more
wiley +1 more source
Research and Practice in Thrombosis and Haemostasis, 2019 Essentials Acquired hemophilia A is a rare bleeding disorder often accompanied by other comorbidities. We describe emicizumab use in acquired hemophilia A complicated by acute coronary syndrome.
Kathryn E. Dane +5 more
doaj +1 more source