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Acquired inhibitors of coagulation are a group of rare but potentially life-threatening blood disorders characterized by the presence of autoantibodies directed against clotting factor. Autoantibody against factor VIII is the most common form of clotting factor inhibitor, a condition also known as acquired hemophilia A.
Yadav, Pandey +4 more
core +8 more sources
WHOLE GENOME SEQUENCE OF SARS-COV-2 FROM COVID-19 ACQUIRED HEMOPHILIA PATIENT
Intro: Acquired hemophilia is an atypical pathology of SARS-CoV-2 infection, which could be variant associated. Here, we share a sequence of the SARS-CoV-2 genome from patient with COVID-19 acquired haemophilia.
U.A. Zainulabid +6 more
doaj +2 more sources
Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs.
Franchini M, LIPPI, Giuseppe
openaire +3 more sources
Diagnosis and Treatment of Acquired Hemophilia A (AHA) with Bullous Pemphigoid [PDF]
Acquired hemophilia A is a condition in which coagulation factor VIII become inactive due to autoantibody formation. This condition is related to pregnancy, malignancy, and autoimmune disease with skin disorder. In this case report, a 66 years woman with
Rasco Sandy Sihombing +7 more
doaj +2 more sources
Acquired Hemophilia A and urothelial carcinoma [PDF]
Acquired Hemophilia A (AHA) is a rare entity, resulting from the production of autoantibodies against Factor VIII of the coagulation cascade. These autoantibodies may develop in response to autoimmune conditions, drugs, neoplastic diseases, and pregnancy.
Fadi Taza +3 more
doaj +3 more sources
Acquired hemophilia A: emerging treatment options
Maissaa Janbain,1 Cindy A Leissinger,1 Rebecca Kruse-Jarres2 1Louisiana Center for Bleeding and Clotting Disorders, Tulane University Medical Center, New Orleans, LA, USA; 2Washington Center for Bleeding Disorders, Blood Works NW, Seattle, WA, USA ...
Janbain M, Leissinger CA, Kruse-Jarres R
doaj +1 more source
Acquired hemophilia is a rare coagulation, due to the presence of autoantibodies directed against acquired factor VIII. It remains idiopathic in almost half the cases, as in other cases, various etiologies are responsible, including some autoimmune diseases.
Kaul, Anita, Palmer, Martin
+7 more sources
Acquired hemophilia (AH) is an autoimmune hemostatic disorder mediated by autoantibodies directed against factor VIII: C. In 52% of cases, the cause is unknown or is not associated with other pathological entities; in the rest, there are concomitant factors: lupus, rheumatoid arthritis, cancer, pregnancy, and medications.
Jaime, García-Chávez +1 more
openaire +2 more sources
The management of hemophilia in elderly patients
Massimo Franchini1, Annarita Tagliaferri2, Pier Mannuccio Mannucci31Transfusion and Hemophilia Center, City Hospital of Verona, Italy; 2Regional Reference Center for Inherited Bleeding Disorders, University Hospital of Parma, Italy; 3Angelo Bianchi ...
Massimo Franchini +2 more
doaj +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source

