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Acquired Immunity to Systemic Candidiasis in Immunodeficient Mice [PDF]

open access: possibleJournal of Infectious Diseases, 1991
Twenty-seven percent of beige-athymic (bg/bg nu/nu) mice died of systemic candidiasis 7-20 weeks after gastrointestinal tract colonization with Candida albicans. Conversely, beige-euthymic (bg/bg nu/+) mice colonized with C. albicans for a similar time period did not die or develop systemic candidiasis. C. albicans-colonized bg/bg nu/+ mice, but not bg/
Edward Balish, Margherita T. Cantorna
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Acquired TTP: ADAMTS13 meets the immune system

Blood Reviews, 2014
The majority of the patients affected by acquired thrombotic thrombocytopenic purpura (TTP) develop autoantibodies directed towards ADAMTS13 that interfere with its von Willebrand Factor (VWF) processing activity. B cell responses have been shown to primarily target the spacer domain of ADAMTS13 thereby prohibiting the binding of ADAMTS13 to the VWF A2
Fabian C. Verbij   +3 more
openaire   +3 more sources

Regulation of Acquired Immune System by Notch Signaling

International Journal of Hematology, 2005
T- and B-cells are generated from hematopoietic stem cells through lymphoid intermediates. The interplay of intrinsic and extrinsic signals determines cell fate at the branch point for T- and B-cell lineages and at the post-commitment stage of lymphogenesis.
Yoshiaki Minato, Koji Yasutomo
openaire   +3 more sources

Systemic sarcocystosis in a patient with acquired immune deficiency syndrome

Human Pathology, 2008
Sarcocystis sp is a tissue coccidian parasite in humans that causes intestinal and muscular sarcocystosis in immunocompetent patients. Intestinal sarcocystosis can be diagnosed at the tissue level in the lamina propria of the small bowel and by fecal examination. Muscular sarcocystosis is diagnosed by microscopic examination of muscle biopsies.
Silvana Carnevale   +7 more
openaire   +3 more sources

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