Chinese expert consensus on the application of intravenous immunoglobulin in hematological diseases. [PDF]
Guo Z+32 more
europepmc +1 more source
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner+5 more
wiley +1 more source
Progress in the development of cancer vaccines for lung cancer utilizing dendritic cells (Review). [PDF]
Hu H, Chen WJ, Sun C, Xie JP.
europepmc +1 more source
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie+5 more
wiley +1 more source
Reported Cases and Deaths of National Notifiable Infectious Diseases - China, November 2024. [PDF]
europepmc +1 more source
Imine Crosslinked, Injectable, and Self‐Healing Fucoidan Hydrogel with Immunomodulatory Properties
This study develops an injectable fucoidan‐based hydrogel with tunable properties for tissue engineering. By oxidizing fucoidan (OFu) to introduce aldehydes, imine crosslinks are formed with amine‐containing polymers, enabling self‐healing, injectability, and long‐term stability (≥28 days). The OFu‐gelatin hydrogel demonstrated biocompatibility, immune‐
Asma Talib Qureshi+3 more
wiley +1 more source
USP21 is involved in the development of chronic hepatitis B by modulating the immune microenvironment. [PDF]
Luo P+7 more
europepmc +1 more source
Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche
Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson+3 more
wiley +1 more source
Reported Cases and Deaths of National Notifiable Infectious Diseases - China, October 2024. [PDF]
europepmc +1 more source
The complex immune puzzle: A deeper dive into the MORC1-mediated broad-spectrum defense signaling pathway. [PDF]
Singla-Rastogi M.
europepmc +1 more source