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Regulation of Acquired Immune System by Notch Signaling

International Journal of Hematology, 2005
T- and B-cells are generated from hematopoietic stem cells through lymphoid intermediates. The interplay of intrinsic and extrinsic signals determines cell fate at the branch point for T- and B-cell lineages and at the post-commitment stage of lymphogenesis.
Y. Minato, K. Yasutomo
semanticscholar   +4 more sources

Why did the acquired immune system of vertebrates evolve?

Developmental & Comparative Immunology, 2007
Rapidly expanding genomic information offers important insights into the mechanisms of acquired immunity and has fostered progress in comparative immunology. However, the question of why the acquired immune system, a trait restricted to jawed vertebrates, evolved has rarely been addressed.
J. Rolff
semanticscholar   +4 more sources

Do all creatures possess an acquired immune system of some sort?

BioEssays, 2014
Recent findings have provided evidence for the existence of non-vertebrate acquired immunity. We survey these findings and propose that all living organisms must express both innate and acquired immunity.
Jacob Rimer, I. Cohen, N. Friedman
semanticscholar   +4 more sources

Cytomegalovirus in the nervous system of patients with the acquired immune deficiency syndrome.

Brain, 1989
Clinicopathological features of infection of the nervous system by cytomegalovirus (CMV) in 31 patients with the acquired immune deficiency syndrome (AIDS) are reviewed.
H. Vinters   +6 more
semanticscholar   +4 more sources

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