Results 51 to 60 of about 286,389 (401)

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Chinese Guideline for Diagnosis and Treatment of Human Immunodeficiency Virus Infection/Acquired Immunodeficiency Syndrome (2024 Edition)

Xiehe Yixue Zazhi
In 2005, the Acquired Immunodeficiency Syndrome Professional Group of Society of Infectious Diseases, Chinese Medical Association formulated the "Guideline for Diagnosis and Treatment of AIDS" in China (hereinafter referred to as the "Guideline").
Acquired Immunodeficiency Syndrome Professional Group of Society of Infectious Diseases, Chinese Medical Association, Chinese Center for Disease Control and Prevention   +1 more
doaj   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Lymph node co-infection of Mycobacterium avium complex and cytomegalovirus in an acquired immunodeficiency syndrome patient

Infectious Disease Reports, 2013
Acquired immunodeficiency syndrome patients are known to have an increased tendency for developing opportunistic infections. However, there are no reports of simultaneous lymph node involvement of cytomegalovirus and Mycobacterium avium complex in a ...
Arya Hedjazi, Marzieh Hosseini, Amin Hoseinzadeh   +2 more
doaj   +1 more source

Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome.

New England Journal of Medicine, 1992
BACKGROUND AND METHODS Toxoplasmosis is the most common opportunistic infection of the central nervous system in patients with the acquired immunodeficiency syndrome (AIDS). To investigate its clinical course, we reviewed the records of 115 patients with
S. Porter, M. Sande
semanticscholar   +1 more source

Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR

Advanced Science, EarlyView.
The tumor microenvironment supports colorectal cancer (CRC) progression by maintaining cancer stem cells (CSCs) through progastrin (PG). This study identifies Protein Zero‐Related protein (PZR) as an essential receptor for PG activity, promoting CSC‐like signaling via SHP2/SRC/β‐catenin.
Julie Nguyen, Marie Lafitte, Maud Barbery, Kevin Espie, Maya Jeitany, Romain Larive, Jihane Vitre, Conception Paul, Yvan Boublik, Elise Fourgous, Valérie Simon, Audrey Sirvent, Madeline Neiveyans, Steeve Thirard, Lucile Bansard, Morgan Maillard, Nathalie Coutry, Jacques Colinge, Philippe Jay, Pierre Martineau, Michael Hahne, Julie Pannequin, Serge Roche   +22 more
wiley   +1 more source

Factors impacting antiretroviral therapy adherence among human immunodeficiency virus-positive adolescents in Sub-Saharan Africa: a systematic review [PDF]

, 2018
© 2018 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.Objectives: Eighty-two percent of human immunodeficiency virus (HIV)–positive adolescents live in Sub-Saharan Africa (SSA).
Adejumo, Agwu, AIDS.gov, AIDSinfo, AIDSinfo, Ankrah, Bernays, Bezabhe, Bhattacharya, Bikaako-Kajura, Birungi, Braitstein, Bygrave, Centers for Disease Control and Prevention, Cluver, Cohen, Critical Appraisal Skills Programme, Danford, Deeks, Denison, Fair, Famoroti, Ferrara, Fetzer, Finocchario-Kessler, Fongkaew, Gross, Gulick, Haberer, Habib, Harries, Hodgson, Hogwood, Hudelson, J.M. Corkery, Jaspan, Joint United Nations Programme on HIV/AIDS, Katz, Kawuma, Kim, King, Kirk, Klitzman, Krauss, Kunapareddy, Lall, Langat, Lowenthal, Lyimo, Maartens, MacPherson, Manglos, Mavhu, Mbirimtengerenji, Mburu, Mburu, Michaud, Mills, Moon, Murphy, Musumari, Mutumba, Mutwa, N. Ammon, Nabukeera-Barungi, Nachega, Nachega, Nachega, Nachega, National Institutes of Health, Nyogea, Nöstlinger, O'Brien, Park, Preferred Reporting Items for Systematic Reviews and Meta-Analyses, Reda, Reisner, Remien, Roberts, Ross-Degnan, S. Mason, Scanlon, Simoni, Sithole, Siu, Sivapalasingam, Thomas, Tumwine, United Nations International Children's Emergency Fund, United Nations International Children's Emergency Fund, Vaz, Vreeman, Vreeman, Vyas, Wanyama, Wasti, Watt, Wiener, World Health Organization, World Health Organization, World Health Organization, World Health Organization, Zou   +102 more
core   +2 more sources

Perspectives on the Current and Future State of Artificial Intelligence in Medical Genetics

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transforming numerous aspects of daily life, including clinical practice and biomedical research. In light of this rapid transformation, and in the context of medical genetics, we assembled a group of leaders in the field to respond to the question about how AI is affecting, and especially how AI will ...
Benjamin D. Solomon, Morgan Cheatham, Thales A. C. de Guimarães, Dat Duong, Melissa A. Haendel, Tzung‐Chien Hsieh, Behnam Javanmardi, Britt Johnson, Peter Krawitz, Paul Kruszka, Tim Laurent, Ni‐Chung Lee, Kirsty McWalter, Michel Michaelides, Klaus Mohnike, Nikolas Pontikos, Maria J. Guillen Sacoto, Yousif J. Shwetar, Vincent D. Ustach, Rebekah L. Waikel, William Woof   +20 more
wiley   +1 more source

Genome Sequencing Uncovers Additional Findings in Phelan‐McDermid Syndrome

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Phelan‐McDermid syndrome (PMS) is a genetic condition caused by deletions of chromosome 22q13.3 or pathogenic variants in the SHANK3 gene. Neurologic features typically include intellectual disability, autism spectrum disorder, hypotonia, and absent speech, though there is considerable variability even among individuals with the same molecular
Rachel Gore Moses, Morgan Similuk, Alexandra Hehn, Rylee Duncan, Margaret Pekar, Eliza Gordon‐Lipkin, Maria T. Acosta, Deena Zeltser, Nadjalisse Reynolds‐Lallement, Latha Soorya, Mustafa Sahin, Tess Levy, Alexander Kolevzon, Joseph D. Buxbaum, Elizabeth Berry‐Kravis, Craig M. Powell, Jonathan A. Bernstein, Mari Tokita, Bryce A. Seifert, Rajarshi Ghosh, Magdalena A. Walkiewicz, Audrey Thurm   +21 more
wiley   +1 more source

Aplastic anemia associated to systemic lupus erythematosus in an AIDS patient: a case report

Revista Brasileira de Hematologia e Hemoterapia, 2013
Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes ...
Leonardo Rodrigues de Oliveira, Thais Camargos Ferreira, Fernando de Freitas Neves, Antonio Carlos de Oliveira Meneses   +3 more
doaj   +1 more source