Results 1 to 10 of about 181 (104)

Utility of Zebrafish Models of Acquired and Inherited Long QT Syndrome [PDF]

Frontiers in Physiology, 2021
Long-QT Syndrome (LQTS) is a cardiac electrical disorder, distinguished by irregular heart rates and sudden death. Accounting for ∼40% of cases, LQTS Type 2 (LQTS2), is caused by defects in the Kv11.1 (hERG) potassium channel that is critical for cardiac
Kyle E. Simpson, Ravichandra Venkateshappa, Zhao Kai Pang, Shoaib Faizi, Glen F. Tibbits, Glen F. Tibbits, Tom W. Claydon   +6 more
doaj   +7 more sources

Acquired long QT syndrome caused by pseudohypoparathyroidism

Наука и инновации в медицине, 2020
The article presents a review of literature data on the long QT syndrome (LQTS), focusing on the role of secondary factors in the development of this disorder.
L. A. Balykova, E. S. Samoshkina, Yu. A. Petrushkina, T. M. Zolnikova, A. V. Krasnopolskaya, S. I. Blohina   +5 more
doaj   +3 more sources

Long QT in stunned myocardium: unrecognised cause of acquired long QT syndrome

Journal of Medical Science, 2014
Long QT syndrome (LQTS) is a heart disorder characterized by a prolongation of the QT interval on ECG and a predisposition to ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest or sudden cardiac death. This condition may be inherited
Jerzy Sacha
doaj   +3 more sources

Acquired long QT syndrome in chronic kidney disease patients

Renal Failure, 2020
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in chronic kidney disease (CKD) patients. QT interval prolongation is a congenital or acquired condition that is associated with an increased risk of torsade de pointes (TdP ...
Peng Liu, Lu Wang, Dan Han, Chaofeng Sun, Xiaolin Xue, Guoliang Li   +5 more
doaj   +2 more sources

Acquired Long QT Syndrome and Electrophysiology of Torsade de Pointes

Arrhythmia & Electrophysiology Review, 2019
Congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. Although congenital LQTS remains the domain of cardiologists, cardiac electrophysiologists and specialised centres, the much more frequently acquired LQTS is the domain of physicians and other members of healthcare teams required to make therapeutic decisions ...
Nabil El-Sherif, Gioia Turitto, Mohamed Boutjdir   +2 more
doaj   +3 more sources

Genetics of acquired long QT syndrome [PDF]

Journal of Clinical Investigation, 2005
The QT interval is the electrocardiographic manifestation of ventricular repolarization, is variable under physiologic conditions, and is measurably prolonged by many drugs. Rarely, however, individuals with normal base-line intervals may display exaggerated QT interval prolongation, and the potentially fatal polymorphic ventricular tachycardia torsade
Dan M, Roden, Prakash C, Viswanathan
openaire   +2 more sources

Congenital and acquired long QT syndrome [PDF]

European Heart Journal, 2000
There is considerable contemporary interest in ventricular repolarization, since prolonged repolarization, especially when heterogeneous, is associated with ventricular tachyarrhythmias, syncope and sudden death. Delayed ventricular repolarization occurs as a congenital anomaly or may be acquired, for example because of the effect of medications on ...
A J, Camm, M J, Janse, D M, Roden, M R, Rosen, J, Cinca, S M, Cobbe   +5 more
openaire   +2 more sources

Initiation of ventricular arrhythmia in the acquired long QT syndrome [PDF]

Cardiovascular Research, 2022
AbstractAimsLong QT syndrome (LQTS) carries a risk of life-threatening polymorphic ventricular tachycardia (Torsades de Pointes, TdP) and is a major cause of premature sudden cardiac death. TdP is induced by R-on-T premature ventricular complexes (PVCs), thought to be generated by cellular early-afterdepolarisations (EADs).
Cherry Alexander, Martin J Bishop, Rebecca J Gilchrist, Francis L Burton, Godfrey L Smith, Rachel C Myles   +5 more
openaire   +2 more sources

Extremely dangerous hypopituitarism related long QT syndrome and transient ST-segment elevation: A case report

SAGE Open Medical Case Reports, 2023
Acquired long QT syndrome caused by hypopituitarism and transient ST-segment elevation has not been reported in cardiac arrest patients. We report a case of extremely dangerous acquired long QT syndrome and transient ST-segment elevation.
Jia Zhang, Yingying Zou, Xiaoshu Chen, Jingye Pan, Haizhu Yu, Yi Wang, Yanran Wu, He Zou   +7 more
doaj   +1 more source

Vomiting, electrolyte disturbance, and medications; the perfect storm for acquired long QT syndrome and cardiac arrest: a case report

Journal of Medical Case Reports, 2022
Background Acquired long QT syndrome is an important and preventable cause of cardiac arrest. Certain medications and electrolyte disturbance are common contributors, and often coexist. In this case, we report five contributors to cardiac arrest.
K. D. Tiver, D. Dharmaprani, J. X. Quah, A. Lahiri, K. E. Waddell-Smith, A. N. Ganesan   +5 more
doaj   +1 more source