Results 131 to 140 of about 3,371,569 (315)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Today Acquisition Challenges [PDF]
, 2011 Symposium Presentation (for Acquisition Research Program)Approved for public release; distribution is unlimited.Acquisition Research ...
Spruill, Nancy
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Results in PhysicsThis paper proposes a joint demodulation and decoding scheme for orbital angular momentum shift keying free-space optical (OAM-SK-FSO) communication systems, termed ViT-Polar, which deeply integrates a Vision Transformer (ViT) with Polar coding to ...
Zihan Shen +7 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Acquisition Research: The Foundation for Innovation [PDF]
, 2005 Proceedings Paper (for Acquisition Research Program)Proceedings of the 2nd Annual Acquisition Research SymposiumA close tie exists between defense acquisition practice and acquisition training.
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Remote SensingThe widespread deployment of unmanned aerial vehicles (UAVs) in civil and commercial airspace has raised significant safety concerns, driving the demand for reliable and real-time Anti-UAV visual detection systems.
Li Pan +8 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Organizational Behavior in Acquisition Organizations [PDF]
, 2007 Symposium Presentation (for Acquisition Research Program)Approved for public release; distribution is unlimited.Naval Postgraduate School Acquisition Research ...
Miller, Kenneth E.
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
First Annual Acquisition Research Symposium Proceedings [PDF]
, 2004 Many in the Department of Defense associate the phase "acquisition reform" with major policy and legislative initiatives of the past decade, for example, the shift away from reliance on military unique specifications and standards, the emphasis on ...
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