Results 81 to 90 of about 7,001,268 (342)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Portfolio Allocation for Bayesian Optimization [PDF]
, 2011 Bayesian optimization with Gaussian processes has become an increasingly popular tool in the machine learning community. It is efficient and can be used when very little is known about the objective function, making it popular in expensive black-box ...
Brochu, Eric +2 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
IEEE Access, 2019 This study proposes a miniature and highly sensitive Fabry-Perot interferometer (FPI) based on aluminum - polyimide diaphragm integrated with a mass block for acceleration sensing. The composite diaphragms with a radius and thickness of 3.5 mm and 630 nm
Shili Li +5 more
doaj +1 more source
Languages, 2020 The present study deals with the perception (identification and discrimination) of an English phonemic contrast (/t∫/–/∫/, as in cheat and sheet) by speakers of two Mexican varieties of Spanish who are learning English as a foreign language.
Mariela López Velarde, Miquel Simonet
doaj +1 more source
Ecological Theory of Language Acquisition [PDF]
, 2004 This poster outlines an Ecological Theory of Language Acquisition (ETLA). The theory views the early phases of the language acquisition process as an emergent consequence of the interaction between the infant and its linguistic environment.
Gustavsson, Lisa +5 more
core
Nature Communications, 2018 Data independent acquisition (DIA) mass spectrometry is a powerful technique that is improving the reproducibility and throughput of proteomics studies.
B. Searle +7 more
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Remote controlled partial discharge acquisition unit [PDF]
, 2003 Online partial discharge (PD) analysis for underground high voltage cables has major advantages over the offline techniques. Online techniques usually involve PD data acquisition, storage and post-processing of the data.
Foo, M.H. +3 more
core